Kawasaki disease: Difference between revisions
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*"Warm CREAM" mnemonic: fever plus conjunctivitis, rash, extremity involvement, adenopathy, and mucosal involvement |
*"Warm CREAM" mnemonic: fever plus conjunctivitis, rash, extremity involvement, adenopathy, and mucosal involvement |
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| − | *Fever persisting at least 5 |
+ | *Fever persisting at least 5 days, with at least 4 principal features: |
**Changes in extremities |
**Changes in extremities |
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***Acute: Erythema of palms, soles; edema of hands, feet |
***Acute: Erythema of palms, soles; edema of hands, feet |
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Revision as of 18:43, 27 September 2023
Diagnostic Criteria
- "Warm CREAM" mnemonic: fever plus conjunctivitis, rash, extremity involvement, adenopathy, and mucosal involvement
- Fever persisting at least 5 days, with at least 4 principal features:
- Changes in extremities
- Acute: Erythema of palms, soles; edema of hands, feet
- Subacute: Periungual peeling of fingers, toes in weeks 2 and 3
- Polymorphous exanthem
- Bilateral bulbar conjunctival injection without exudate
- Changes in lips and oral cavity: Erythema, lips cracking, strawberry tongue, diffuse injection of oral and pharyngeal mucosae
- Cervical lymphadenopathy (>1.5-cm diameter), usually unilateral
- Changes in extremities
- Exclusion of other diseases with similar findings‡
Incomplete Kawasaki disease
- Do not meet the full criteria above
Differential Diagnosis
- Viral infections: measles, adenovirus, enterovirus, Epstein-Barr virus
- Scarlet fever
- Staphylococcal scalded skin syndrome
- Toxic shock syndrome
- Bacterial cervical lymphadenitis
- Drug hypersensitivity reactions
- Stevens-Johnson syndrome
- Juvenile rheumatoid arthritis
- Rocky Mountain spotted fever
- Leptospirosis
- Mercury hypersensitivity reaction (acrodynia)
