Inflammatory bowel disease: Difference between revisions

Revision as of 15:00, 5 August 2020

	Ulcerative colitis	Crohn disease
Location	Pancolitis (30%) Proctosigmoiditis (50%) Includes PSC (5%)	Terminal ileum (80%) Ileocolonic (50%) Isolated ileal (30%) Isolated colonic (20%)
Distribution	Continuous from rectum	Skip lesions, often rectum-sparing
Histology	Mucosal inflammation without granulomas	Transmural inflammation, granulomas, cobblestone
Serology	p-ANCA	Anti-Saccharomyces cervisiae IgG
Complications	Toxic megacolon Colorectal cancer	Intraabdominal abscess, perforation, fistulae, strictures, perianal disease, obstruction, colorectal cancer

Extraintestinal Manifestations

MSK
- Seronegative spondyloarthritis
- Osteopenia
Dermatologic
- Erythema nodosum
- Pyoderma gangrenosum
Opthalmologic
- Episcleritis
- Uveitis
Clubbing
Renal
- Kidney stones
Hepatobiliary
- Gallstones
- Primary sclerosing cholangitis
Hematologic
Aphthous ulcers

Arthritis

Type 1: Pauciarticular

<5 joints
Large joints
Short duration
Correlates with disease activity

Type 2: Polyarticular

>5 joints
Small joints
Months to years
Independent of disease activity

@@ Line 1: / Line 1: @@
+{| class="wikitable"
-* [[Ulcerative colitis]]
-* [[Crohn disease]]
-{|
 !
-! Ulcerative colitis
+![[Ulcerative colitis]]
-! Crohn disease
+![[Crohn disease]]
 |-
-| Location
+|Location
-| Pancolitis (30%)<br/>Proctosigmoiditis (50%)<br/>Includes PSC (5%)
+|[[Pancolitis]] (30%)<br />[[Proctosigmoiditis]] (50%)<br />Includes [[PSC]] (5%)
-| Terminal ileum (80%)<br/>Ileocolonic (50%)<br/>Isolated ildeal (30%)<br/>Isolated colonic (20%)
+|Terminal ileum (80%)<br />Ileocolonic (50%)<br />Isolated ileal (30%)<br />Isolated colonic (20%)
 |-
-| Distribution
+|Distribution
-| Continuous from rectum
+|Continuous from rectum
-| Skip lesions, often rectum-sparing
+|Skip lesions, often rectum-sparing
 |-
-| Histology
+|Histology
-| Mucosal inflammation without granulomas
+|Mucosal inflammation without granulomas
-| Transmural inflammation, granulomas, cobblestone
+|Transmural inflammation, granulomas, cobblestone
 |-
-| Serology
+|Serology
-| p-ANCA
+|p-ANCA
-| Anti-Saccharomyces cervisiae IgG
+|Anti-Saccharomyces cervisiae IgG
 |-
-| Complications
+|Complications
-| Toxic megacolon<br/>Colorectal cancer
+|[[Toxic megacolon]]<br />[[Colorectal cancer]]
-| Abscesses, perforation, fistulae, strictures, perianal disease, obstruction, colorectal cancer
+|[[Intra-abdominal infections|Intraabdominal abscess]], perforation, fistulae, strictures, perianal disease, obstruction, [[colorectal cancer]]
 |}
-== Extraintestinal Manifestations ==
+==Extraintestinal Manifestations==
-* MSK
+*MSK
-** Seronegative spondyloarthritis
+**[[Seronegative spondyloarthritis]]
-** Osteopenia
+**[[Osteopenia]]
-* Dermatologic
+*Dermatologic
-** Erythema nodosum
+**[[Erythema nodosum]]
-** Pyoderma gangrenosum
+**[[Pyoderma gangrenosum]]
-* Opthalmologic
+*Opthalmologic
-** Episcleritis
+**[[Episcleritis]]
-** Uveitis
+**[[Uveitis]]
-* Clubbing
+*[[Clubbing]]
-* Renal
+*Renal
-** Kidney stones
+**[[Kidney stone|Kidney stones]]
-* Hepatobiliary
+*Hepatobiliary
-** Gallstones
+**[[Gallstone|Gallstones]]
-** Primary sclerosing cholangitis
+**[[Primary sclerosing cholangitis]]
-* Hematologic
+*Hematologic
-** DVT
+**[[DVT]]
-** Amyloidosis
+**[[Amyloidosis]]
-** Anemia (iron-deficiency, chronic inflammatory, B12 deficiency)
+**[[Anemia]] ([[Iron-deficiency anemia|iron-deficiency]], [[Anemia of chronic inflammation|chronic inflammatory]], [[Vitamin B12 deficiency|B12 deficiency]])
-* Aphthous ulcers
+*[[Aphthous ulcer|Aphthous ulcers]]
-=== Arthritis ===
+===Arthritis===
-==== Type 1: Pauciarticular ====
+====Type 1: Pauciarticular====
-* &lt;5 joints
+*&lt;5 joints
-* Large joints
+*Large joints
-* Short duration
+*Short duration
-* Correlates with disease activity
+*Correlates with disease activity
-==== Type 2: Polyarticular ====
+====Type 2: Polyarticular====
-* &gt;5 joints
+*&gt;5 joints
-* Small joints
+*Small joints
-* Months to years
+*Months to years
-* Independent of disease activity
+*Independent of disease activity
 [[Category:Gastroenterology]]