Uveitis
From IDWiki
Background
- Inflammation of the uvea, which comprises the iris, ciliary body, and choroid, or of the retina
- Anterior: iritis, iridocyclitis
- Intermediate: pars planitis
- Posterior: choroiditis, retinitis, chorioretinitis
- Panuveitis
Differential Diagnosis
Infectious causes
- Anterior uveitis (10% infectious)
- Herpes simplex virus (by far the most common infectious cause)
- Varicella-zoster virus
- Syphilis
- Tuberculosis
- Lyme disease
- Leprosy
- Intermediate uveitis (rarely infectious)
- Posterior uveitis (50% infectious)
- Toxoplasmosis
- Acute retinal necrosis from HSV, VZV, and CMV
- CMV retinitis, in immunocompromised patients
- Toxocara
- Syphilis
- Cat-scratch disease
- Candida endophthalmitis
- West Nile virus, causing a multifocal chorioretinitis
- Panuveitis
- Syphilis
- Tuberculosis
- Candida endophthalmitis
- Leptospirosis, without retinal or choroidal lesions
- Other
- Brucella, causing a chronic relapsing uveitis that is typically posterior but can be anterior or panuveitis1
- Chikungunya
- Ebola virus
- Zika virus
Clinical Manifestations
- Anterior: painful red eye and vision loss
- Intermediate: vision loss with floaters, usually painless (and rarely infectious)
- Posterior: painless vision loss
References
- ^ Isaias Rolando, Liset Olarte, Gustavo Vilchez, Marina Lluncor, Larissa Otero, Mark Paris, Carlos Carrillo, Eduardo Gotuzzo. Ocular Manifestations Associated with Brucellosis: A 26‐Year Experience in Peru. Clinical Infectious Diseases. 2008;46(9):1338-1345. doi:10.1086/529442.