Guillain-Barré syndrome: Difference between revisions
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+ | == Background == |
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| + | * Causes either acute inflammatory demyelinating polyneuropathy, or acute motor axonal neuropathy, or acute motor and sensory axonal neuropathy |
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| + | ===Etiology=== |
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| + | === Epidemiology === |
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| + | * About 1 case per 100,000 people per year in Western countries |
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| + | == Clinical Manifestations == |
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| + | * Ascending paralysis ± sensory involvement |
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| + | * Usually occurs 1 to 2 weeks after an immune-stimulating even such as illness or vaccination |
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| + | ** Preceding illness usually a gastrointestinal or respiratory infection |
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| + | ** [[Campylobacter jejuni]] is the most common causative organism identified |
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| + | ** Rare following influenza vaccination; most notable was the 1976 H1N1 vaccine, with about 1 in 100,000 vaccine recipients developing GBS |
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| + | == Further Reading == |
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| + | * Guillain-Barré syndrome. ''Lancet''. 2016;388:717-727. doi: [https://doi.org/10.1016/S0140-6736(16)00339-1 10.1016/S0140-6736(16)00339-1] |
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| + | [[Category:Neurology]] |
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| + | [[Category:Infectious diseases]] |
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Revision as of 21:42, 13 July 2020
Background
- Causes either acute inflammatory demyelinating polyneuropathy, or acute motor axonal neuropathy, or acute motor and sensory axonal neuropathy
Etiology
- Campylobacter jejuni
- Cytomegalovirus
- Epstein-Barr virus
- Zika virus
- HIV
- Non-infectious causes, including immunization, surgery, trauma, and hematopoietic stem cell transplantation
Epidemiology
- About 1 case per 100,000 people per year in Western countries
Clinical Manifestations
- Ascending paralysis ± sensory involvement
- Usually occurs 1 to 2 weeks after an immune-stimulating even such as illness or vaccination
- Preceding illness usually a gastrointestinal or respiratory infection
- Campylobacter jejuni is the most common causative organism identified
- Rare following influenza vaccination; most notable was the 1976 H1N1 vaccine, with about 1 in 100,000 vaccine recipients developing GBS
Further Reading
- Guillain-Barré syndrome. Lancet. 2016;388:717-727. doi: 10.1016/S0140-6736(16)00339-1
