Dengue virus: Difference between revisions
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− | == |
+ | ==Background== |
− | === |
+ | ===Microbiology=== |
*Single-stranded positive-sense RNA virus |
*Single-stranded positive-sense RNA virus |
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*Member of the [[Flaviviridae]] |
*Member of the [[Flaviviridae]] |
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− | === |
+ | ===Epidemiology=== |
− | * |
+ | *Endemic in tropics worldwide, with almost half of the world's population at risk of infection |
− | * |
+ | *Transmitted by ''[[Vector::Aedes aegypti]]'' and ''[[Vector::Aedes albopictus]]'' |
− | == |
+ | ==Clinical Manifestations== |
*Incubation period of [[Usual incubation period::4 to 7 days]] |
*Incubation period of [[Usual incubation period::4 to 7 days]] |
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*Classic presentation includes [[Causes::fever]], [[Causes::headache]] (especially retroorbital), diffuse [[Causes::arthralgias]] ("breakbone fever"), and [[Causes::rash]] |
*Classic presentation includes [[Causes::fever]], [[Causes::headache]] (especially retroorbital), diffuse [[Causes::arthralgias]] ("breakbone fever"), and [[Causes::rash]] |
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*Often has [[Causes::thrombocytopenia]] |
*Often has [[Causes::thrombocytopenia]] |
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+ | *With repeated infections, can progress to [[Causes::hemorrhagic fever]] and [[Causes::shock]] |
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− | == |
+ | ==Differential Diagnosis== |
*Differential also include whichever [[rickettsioses]] are endemic to the area visited |
*Differential also include whichever [[rickettsioses]] are endemic to the area visited |
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+ | {| class="wikitable" |
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⚫ | |||
+ | !Feature |
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+ | !Dengue |
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+ | ![[Zika]] |
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+ | ![[Chikungunya]] |
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+ | |- |
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+ | |Fever |
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+ | | +++ |
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+ | | ++ |
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+ | | +++ |
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+ | |- |
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+ | |Rash |
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+ | | + |
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+ | | +++ |
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+ | | ++ |
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+ | |- |
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+ | |Conjunctivitis |
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+ | |– |
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+ | | ++ |
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+ | |– |
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+ | |- |
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+ | |Arthralgia |
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+ | | + |
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+ | | ++ |
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+ | | +++ |
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+ | |- |
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+ | |Myalgia |
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+ | | ++ |
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+ | | + |
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+ | | + |
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+ | |- |
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+ | |Headache |
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+ | | ++ |
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+ | | + |
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+ | | ++ |
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+ | |- |
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+ | |Hemorrhage |
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+ | | ++ |
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+ | |– |
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+ | |– |
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+ | |- |
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+ | |Shock |
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+ | | + |
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+ | |– |
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+ | |– |
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+ | |} |
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⚫ | |||
⚫ | |||
+ | |||
⚫ | |||
[[Category:Flaviviridae]] |
[[Category:Flaviviridae]] |
Revision as of 13:59, 22 August 2020
Background
Microbiology
- Single-stranded positive-sense RNA virus
- Member of the Flaviviridae
Epidemiology
- Endemic in tropics worldwide, with almost half of the world's population at risk of infection
- Transmitted by Aedes aegypti and Aedes albopictus
Clinical Manifestations
- Incubation period of 4 to 7 days
- Classic presentation includes fever, headache (especially retroorbital), diffuse arthralgias ("breakbone fever"), and rash
- Often has thrombocytopenia
- With repeated infections, can progress to hemorrhagic fever and shock
Differential Diagnosis
- Differential also include whichever rickettsioses are endemic to the area visited
Feature | Dengue | Zika | Chikungunya |
---|---|---|---|
Fever | +++ | ++ | +++ |
Rash | + | +++ | ++ |
Conjunctivitis | – | ++ | – |
Arthralgia | + | ++ | +++ |
Myalgia | ++ | + | + |
Headache | ++ | + | ++ |
Hemorrhage | ++ | – | – |
Shock | + | – | – |
Management
- Supportive