Clostridial toxic shock syndrome
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Revision as of 12:50, 14 December 2021 by Aidan (talk | contribs) (Created page with "== Background == * Toxic shock syndrome caused by Clostridium sordellii == Clinical Manifestations == * Hemoconcentration with high hematocrit and hemoglobin * Capi...")
Background
- Toxic shock syndrome caused by Clostridium sordellii
Clinical Manifestations
- Hemoconcentration with high hematocrit and hemoglobin
- Capillary leak causing edema and ascites
- Leukemoid reaction
- Often afebrile
Management
- Fluid resuscitation
- Penicillin G 18-20 million units daily divided q4-6h
- Plus clindamycin 900 mg IV q8h for toxin production
