Aplastic anemia

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Background

Pancytopenia with hypocellular bone marrow
May be either acquired or congenital

Differential Diagnosis

Acquired
- Secondary
  - Radiation
  - Drugs and toxins
    - Regular effects
    - Idiosyncratic reactions
  - Viral infections
    - Epstein-Barr virus
    - Non-A, non-B, non-C viral hepatitis
    - Parvovirus B19
    - HIV
  - Immune disorders
    - Eosinophilic fasciitis
    - Hypoimmunoglobulinemia
    - Large granular lymphocytosis
    - Thymoma or thymic carcinoma
    - Graft-versus-host disease
    - Paroxysmal nocturnal hemoglobinuria
    - Pregnancy
- Idiopathic
Congenital or inhereted

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Hematology