Antibiotic spectrum index: Difference between revisions

From IDWiki
m (added links)
(added spectrum table)
Line 5: Line 5:
 
** [[Enterococcus faecalis]]
  
** [[Enterococcus faecalis]]
 
** Vancomycin-resistant [[Enterococcus faecalis]] (VRE)
  
** Vancomycin-resistant [[Enterococcus faecalis]] (VRE)
−
** [[Escherichia coli]] and [[Klebsiella]]
 +
** [[Escherichia coli]] or [[Klebsiella]]
−
** [[AmpC β-lactamase|AmpC producers]]
 +
** [[AmpC β-lactamase|AmpC producers]] ([[Enterobacter]], [[Serratia]], and [[Citrobacter]])
−
** [[Extended-spectrum β-lactamases|Extended-spectrum β-lactamase]] (ESBL) E. coli/Klebsiella
 +
** [[Extended-spectrum β-lactamases|Extended-spectrum β-lactamase]] (ESBL) [[Escherichia coli|E. coli]]/[[Klebsiella]]
 
** [[Pseudomonas aeruginosa]]
  
** [[Pseudomonas aeruginosa]]
 
** Penicillin-resistant [[pneumococcus]] (PRP)
  
** Penicillin-resistant [[pneumococcus]] (PRP)
 
** [[Moraxella]] and [[Haemophilus influenzae]]
  
** [[Moraxella]] and [[Haemophilus influenzae]]
 
** [[Mycoplasma]] and [[Chlamydophila]]
  
** [[Mycoplasma]] and [[Chlamydophila]]
−
** [[Anaerobes]] (1 point; 2 points for [[Bacteriodes fragilis]])
 +
** [[Anaerobes]] (in general)
  +
** [[Bacteriodes fragilis]] (specifically)
  +
** Multidrug-resistant organisms
  +
* For each patient, the number of points for every antibiotic is added to give a total daily ASI
  +
  +
== Spectrum Indices ==
  +
{| class="wikitable"
  +
!Antibiotic
  +
!MSSA
  +
!Enterococcus
  +
!Anaerobes
  +
!Bacteroides
  +
!Moraxella/Haemophilus
  +
!Escherichia/Klebsiella
  +
!AmpC
  +
!ESBL
  +
!Pseudomonas
  +
!MRSA
  +
!Pen-R pneumococcus
  +
!VRE
  +
!Atypical
  +
!MDRO
  +
!ASI
  +
|-
  +
|Dicloxacillin
  +
|1
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|1
  +
|-
  +
|Oxacillin
  +
|1
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|1
  +
|-
  +
|Amoxicillin
  +
|0
  +
|1
  +
|0
  +
|0
  +
|0
  +
|1
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|2
  +
|-
  +
|Ampicillin
  +
|0
  +
|1
  +
|0
  +
|0
  +
|0
  +
|1
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|2
  +
|-
  +
|Cephalexin
  +
|1
  +
|0
  +
|0
  +
|0
  +
|0
  +
|1
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|2
  +
|-
  +
|Erythromycin
  +
|0
  +
|0
  +
|0
  +
|0
  +
|1
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|1
  +
|0
  +
|2
  +
|-
  +
|Erythromycin
  +
|0
  +
|0
  +
|0
  +
|0
  +
|1
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|1
  +
|0
  +
|2
  +
|-
  +
|Metronidazole
  +
|0
  +
|0
  +
|1
  +
|1
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|2
  +
|-
  +
|Penicillin
  +
|0
  +
|1
  +
|1
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|2
  +
|-
  +
|Aztreonam
  +
|0
  +
|0
  +
|0
  +
|0
  +
|1
  +
|1
  +
|0
  +
|0
  +
|1
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|3
  +
|-
  +
|Cefazolin
  +
|1
  +
|0
  +
|0
  +
|0
  +
|1
  +
|1
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|3
  +
|-
  +
|Cefdinir
  +
|1
  +
|0
  +
|0
  +
|0
  +
|1
  +
|1
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|3
  +
|-
  +
|Cefixime
  +
|0
  +
|0
  +
|1
  +
|0
  +
|1
  +
|1
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|3
  +
|-
  +
|Cefpodoxime
  +
|1
  +
|0
  +
|0
  +
|0
  +
|1
  +
|1
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|3
  +
|-
  +
|Rifampin
  +
|1
  +
|0
  +
|0
  +
|0
  +
|1
  +
|0
  +
|0
  +
|0
  +
|0
  +
|1
  +
|0
  +
|0
  +
|0
  +
|0
  +
|3
  +
|-
  +
|Azithromycin
  +
|1
  +
|0
  +
|1
  +
|0
  +
|1
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|1
  +
|0
  +
|4
  +
|-
  +
|Cefprozil
  +
|1
  +
|0
  +
|1
  +
|0
  +
|1
  +
|1
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|4
  +
|-
  +
|Ceftazidime
  +
|0
  +
|0
  +
|1
  +
|0
  +
|1
  +
|1
  +
|0
  +
|0
  +
|1
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|4
  +
|-
  +
|Cefuroxime
  +
|1
  +
|0
  +
|1
  +
|0
  +
|1
  +
|1
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|4
  +
|-
  +
|Chloramphenicol
  +
|0
  +
|0
  +
|1
  +
|1
  +
|1
  +
|1
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|4
  +
|-
  +
|Clarithromycin
  +
|1
  +
|0
  +
|1
  +
|0
  +
|1
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|1
  +
|0
  +
|4
  +
|-
  +
|Clindamycin
  +
|1
  +
|0
  +
|1
  +
|1
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|1
  +
|0
  +
|0
  +
|0
  +
|0
  +
|4
  +
|-
  +
|Piperacillin
  +
|0
  +
|1
  +
|1
  +
|0
  +
|0
  +
|1
  +
|0
  +
|0
  +
|1
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|4
  +
|-
  +
|Trimethoprim- sulfamethoxazole
  +
|1
  +
|0
  +
|0
  +
|0
  +
|1
  +
|1
  +
|0
  +
|0
  +
|0
  +
|1
  +
|0
  +
|0
  +
|0
  +
|0
  +
|4
  +
|-
  +
|Cefotaxime
  +
|1
  +
|0
  +
|1
  +
|0
  +
|1
  +
|1
  +
|0
  +
|0
  +
|0
  +
|0
  +
|1
  +
|0
  +
|0
  +
|0
  +
|5
  +
|-
  +
|Cefoxitin
  +
|1
  +
|0
  +
|1
  +
|1
  +
|1
  +
|1
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|5
  +
|-
  +
|Ceftriaxone
  +
|1
  +
|0
  +
|1
  +
|0
  +
|1
  +
|1
  +
|0
  +
|0
  +
|0
  +
|0
  +
|1
  +
|0
  +
|0
  +
|0
  +
|5
  +
|-
  +
|Colistimethate
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|1
  +
|1
  +
|1
  +
|1
  +
|0
  +
|0
  +
|0
  +
|0
  +
|1
  +
|5
  +
|-
  +
|Daptomycin
  +
|1
  +
|1
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|1
  +
|0
  +
|1
  +
|0
  +
|1
  +
|5
  +
|-
  +
|Doxycycline
  +
|1
  +
|0
  +
|0
  +
|0
  +
|1
  +
|1
  +
|0
  +
|0
  +
|0
  +
|1
  +
|0
  +
|0
  +
|1
  +
|0
  +
|5
  +
|-
  +
|Gentamicin
  +
|1
  +
|0
  +
|0
  +
|0
  +
|1
  +
|1
  +
|0
  +
|0
  +
|1
  +
|1
  +
|0
  +
|0
  +
|0
  +
|0
  +
|5
  +
|-
  +
|Minocycline
  +
|1
  +
|0
  +
|0
  +
|0
  +
|1
  +
|1
  +
|0
  +
|0
  +
|0
  +
|1
  +
|0
  +
|0
  +
|1
  +
|0
  +
|5
  +
|-
  +
|Telavancin
  +
|1
  +
|1
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|1
  +
|1
  +
|0
  +
|0
  +
|1
  +
|5
  +
|-
  +
|Tobramycin
  +
|1
  +
|0
  +
|0
  +
|0
  +
|1
  +
|1
  +
|0
  +
|0
  +
|1
  +
|1
  +
|0
  +
|0
  +
|0
  +
|0
  +
|5
  +
|-
  +
|Vancomycin
  +
|1
  +
|1
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|1
  +
|1
  +
|0
  +
|0
  +
|1
  +
|5
  +
|-
  +
|Amikacin sulfate
  +
|1
  +
|0
  +
|0
  +
|0
  +
|1
  +
|1
  +
|0
  +
|0
  +
|1
  +
|1
  +
|0
  +
|0
  +
|0
  +
|1
  +
|6
  +
|-
  +
|Amoxicillin-clavulanate
  +
|1
  +
|1
  +
|1
  +
|1
  +
|1
  +
|1
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|6
  +
|-
  +
|Ampicillin-sulbactam
  +
|1
  +
|1
  +
|1
  +
|1
  +
|1
  +
|1
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|6
  +
|-
  +
|Cefepime
  +
|1
  +
|0
  +
|0
  +
|0
  +
|1
  +
|1
  +
|1
  +
|0
  +
|1
  +
|0
  +
|1
  +
|0
  +
|0
  +
|0
  +
|6
  +
|-
  +
|Linezolid
  +
|1
  +
|1
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|1
  +
|1
  +
|1
  +
|0
  +
|1
  +
|6
  +
|-
  +
|Ticarcillin-clavulanate
  +
|1
  +
|0
  +
|1
  +
|1
  +
|1
  +
|1
  +
|0
  +
|0
  +
|1
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|6
  +
|-
  +
|Ceftaroline
  +
|1
  +
|1
  +
|0
  +
|0
  +
|1
  +
|1
  +
|1
  +
|0
  +
|0
  +
|1
  +
|1
  +
|0
  +
|0
  +
|1
  +
|8
  +
|-
  +
|Ciprofloxacin
  +
|1
  +
|1
  +
|0
  +
|0
  +
|1
  +
|1
  +
|1
  +
|1
  +
|1
  +
|0
  +
|0
  +
|0
  +
|1
  +
|0
  +
|8
  +
|-
  +
|Piperacillin-tazobactam
  +
|1
  +
|1
  +
|1
  +
|1
  +
|1
  +
|1
  +
|1
  +
|0
  +
|1
  +
|0
  +
|0
  +
|0
  +
|0
  +
|0
  +
|8
  +
|-
  +
|Ertapenem
  +
|1
  +
|0
  +
|1
  +
|1
  +
|1
  +
|1
  +
|1
  +
|1
  +
|0
  +
|0
  +
|1
  +
|0
  +
|0
  +
|1
  +
|9
  +
|-
  +
|Levofloxacin
  +
|1
  +
|1
  +
|1
  +
|0
  +
|1
  +
|1
  +
|1
  +
|1
  +
|0
  +
|0
  +
|1
  +
|0
  +
|1
  +
|0
  +
|9
  +
|-
  +
|Meropenem
  +
|1
  +
|0
  +
|1
  +
|1
  +
|1
  +
|1
  +
|1
  +
|1
  +
|1
  +
|0
  +
|1
  +
|0
  +
|0
  +
|1
  +
|10
  +
|-
  +
|Moxifloxacin
  +
|1
  +
|1
  +
|1
  +
|1
  +
|1
  +
|1
  +
|1
  +
|0
  +
|0
  +
|1
  +
|1
  +
|0
  +
|1
  +
|0
  +
|10
  +
|-
  +
|Imipenem-cilastatin
  +
|1
  +
|1
  +
|1
  +
|1
  +
|1
  +
|1
  +
|1
  +
|1
  +
|1
  +
|0
  +
|1
  +
|0
  +
|0
  +
|1
  +
|11
  +
|-
  +
|Tigecycline
  +
|1
  +
|1
  +
|1
  +
|1
  +
|1
  +
|1
  +
|1
  +
|1
  +
|0
  +
|1
  +
|1
  +
|1
  +
|1
  +
|1
  +
|13
  +
|}
   
 
==Further Reading==
  
==Further Reading==

Revision as of 08:13, 22 September 2022

Spectrum Indices

Antibiotic MSSA Enterococcus Anaerobes Bacteroides Moraxella/Haemophilus Escherichia/Klebsiella AmpC ESBL Pseudomonas MRSA Pen-R pneumococcus VRE Atypical MDRO ASI
Dicloxacillin 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1
Oxacillin 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1
Amoxicillin 0 1 0 0 0 1 0 0 0 0 0 0 0 0 2
Ampicillin 0 1 0 0 0 1 0 0 0 0 0 0 0 0 2
Cephalexin 1 0 0 0 0 1 0 0 0 0 0 0 0 0 2
Erythromycin 0 0 0 0 1 0 0 0 0 0 0 0 1 0 2
Erythromycin 0 0 0 0 1 0 0 0 0 0 0 0 1 0 2
Metronidazole 0 0 1 1 0 0 0 0 0 0 0 0 0 0 2
Penicillin 0 1 1 0 0 0 0 0 0 0 0 0 0 0 2
Aztreonam 0 0 0 0 1 1 0 0 1 0 0 0 0 0 3
Cefazolin 1 0 0 0 1 1 0 0 0 0 0 0 0 0 3
Cefdinir 1 0 0 0 1 1 0 0 0 0 0 0 0 0 3
Cefixime 0 0 1 0 1 1 0 0 0 0 0 0 0 0 3
Cefpodoxime 1 0 0 0 1 1 0 0 0 0 0 0 0 0 3
Rifampin 1 0 0 0 1 0 0 0 0 1 0 0 0 0 3
Azithromycin 1 0 1 0 1 0 0 0 0 0 0 0 1 0 4
Cefprozil 1 0 1 0 1 1 0 0 0 0 0 0 0 0 4
Ceftazidime 0 0 1 0 1 1 0 0 1 0 0 0 0 0 4
Cefuroxime 1 0 1 0 1 1 0 0 0 0 0 0 0 0 4
Chloramphenicol 0 0 1 1 1 1 0 0 0 0 0 0 0 0 4
Clarithromycin 1 0 1 0 1 0 0 0 0 0 0 0 1 0 4
Clindamycin 1 0 1 1 0 0 0 0 0 1 0 0 0 0 4
Piperacillin 0 1 1 0 0 1 0 0 1 0 0 0 0 0 4
Trimethoprim- sulfamethoxazole 1 0 0 0 1 1 0 0 0 1 0 0 0 0 4
Cefotaxime 1 0 1 0 1 1 0 0 0 0 1 0 0 0 5
Cefoxitin 1 0 1 1 1 1 0 0 0 0 0 0 0 0 5
Ceftriaxone 1 0 1 0 1 1 0 0 0 0 1 0 0 0 5
Colistimethate 0 0 0 0 0 1 1 1 1 0 0 0 0 1 5
Daptomycin 1 1 0 0 0 0 0 0 0 1 0 1 0 1 5
Doxycycline 1 0 0 0 1 1 0 0 0 1 0 0 1 0 5
Gentamicin 1 0 0 0 1 1 0 0 1 1 0 0 0 0 5
Minocycline 1 0 0 0 1 1 0 0 0 1 0 0 1 0 5
Telavancin 1 1 0 0 0 0 0 0 0 1 1 0 0 1 5
Tobramycin 1 0 0 0 1 1 0 0 1 1 0 0 0 0 5
Vancomycin 1 1 0 0 0 0 0 0 0 1 1 0 0 1 5
Amikacin sulfate 1 0 0 0 1 1 0 0 1 1 0 0 0 1 6
Amoxicillin-clavulanate 1 1 1 1 1 1 0 0 0 0 0 0 0 0 6
Ampicillin-sulbactam 1 1 1 1 1 1 0 0 0 0 0 0 0 0 6
Cefepime 1 0 0 0 1 1 1 0 1 0 1 0 0 0 6
Linezolid 1 1 0 0 0 0 0 0 0 1 1 1 0 1 6
Ticarcillin-clavulanate 1 0 1 1 1 1 0 0 1 0 0 0 0 0 6
Ceftaroline 1 1 0 0 1 1 1 0 0 1 1 0 0 1 8
Ciprofloxacin 1 1 0 0 1 1 1 1 1 0 0 0 1 0 8
Piperacillin-tazobactam 1 1 1 1 1 1 1 0 1 0 0 0 0 0 8
Ertapenem 1 0 1 1 1 1 1 1 0 0 1 0 0 1 9
Levofloxacin 1 1 1 0 1 1 1 1 0 0 1 0 1 0 9
Meropenem 1 0 1 1 1 1 1 1 1 0 1 0 0 1 10
Moxifloxacin 1 1 1 1 1 1 1 0 0 1 1 0 1 0 10
Imipenem-cilastatin 1 1 1 1 1 1 1 1 1 0 1 0 0 1 11
Tigecycline 1 1 1 1 1 1 1 1 0 1 1 1 1 1 13

Further Reading

  • Development and Application of an Antibiotic Spectrum Index for Benchmarking Antibiotic Selection Patterns Across Hospitals. Infect Control Hosp Epidemiol. 2017;38(8):993-997. doi: 10.1017/ice.2017.94.
Retrieved from "https://idwiki.org/index.php?title=Antibiotic_spectrum_index&oldid=9424"
Powered by MediaWiki
Powered by Semantic MediaWiki