Acquired immunodeficiency: Difference between revisions
From IDWiki
No edit summary |
(moved clinical manifestations table to Immunodeficiency) |
||
| Line 1: | Line 1: | ||
| − | See also [[primary immunodeficiency]] |
+ | * See also [[immunodeficiency]] and [[primary immunodeficiency]] |
==Clinical Manifestations== |
==Clinical Manifestations== |
||
| + | |||
| − | {| class="wikitable" |
||
| + | * See also [[Immunodeficiency#Clinical%20Manifestations|clinical manifestations of immunodeficiency]] |
||
| − | !Immune Defect |
||
| + | |||
| − | !Typical Infections |
||
| − | !Typical Organisms |
||
| − | |- |
||
| − | |cell-mediated (T cells) |
||
| − | |persistent viral infections, opportunistic infections, disseminated infections |
||
| − | |[[Pneumocystis jirovecii]], [[Cryptococcus]], [[Herpesviridae]] |
||
| − | |- |
||
| − | |humoural (B cells) |
||
| − | |respiratory infections with [[Encapsulated bacteria|encapsulated organisms]], [[chronic diarrhea]], [[aseptic meningitis]] |
||
| − | |[[Haemophilus influenzae]], [[Streptococcus pneumoniae]], [[Giardia lamblia]], [[Campylobacter]], [[Enterovirus|enteroviruses]] |
||
| − | |- |
||
| − | |phagocytic |
||
| − | |recurrent [[Abscess|abscesses]], [[gingivitis]], [[Aphthous ulcer|aphthous ulcers]] |
||
| − | |[[Staphylococcus aureus]], [[Burkholderia cepacia]], [[Serratia marcescens]], [[Aspergillus]], [[Nocardia]] |
||
| − | |- |
||
| − | |monocytic |
||
| − | |disseminated infections and multifocal [[osteomyelitis]] |
||
| − | |[[non-tuberculous mycobacteria]], [[Salmonella]], [[Histoplasma capsulatum]], [[Coccidioides immitis]] |
||
| − | |- |
||
| − | |[[Toll-like receptors|TLR]] |
||
| − | |recurrent [[meningitis]], [[bacteremia]], absence of fever |
||
| − | |[[Streptococcus pneumoniae]], [[Neisseria meningitidis]], [[Staphylococcus aureus]], [[HSV]] |
||
| − | |- |
||
| − | |complement |
||
| − | |recurrent [[bacteremia]] and [[meningitis]] |
||
| − | |[[Neisseria]] |
||
| − | |- |
||
| − | |T cells and phagocytes |
||
| − | |[[eczema]], [[kyphoscoliosis]], pathologic fratures, pulmonary and cutaneous infections, [[mucocutaneous candidiasis]] |
||
| − | |[[Staphylococcus aureus]], [[Haemophilus influenzae]], [[Streptococcus pneumoniae]], [[Candida albicans]] |
||
| − | |} |
||
==Differential Diagnosis== |
==Differential Diagnosis== |
||
Latest revision as of 20:08, 15 February 2023
- See also immunodeficiency and primary immunodeficiency
Clinical Manifestations
Differential Diagnosis
Cell-Mediated Immunodeficiency
- Corticosteroids
- Solid organ transplantation
- Hematologic malignancy
- Chemotherapy
- Human immunodeficiency virus
Humoural Immunodeficiency
- Splenectomy and asplenism
- Complement deficiency
- Common variable immunodeficiency
- Rituximab and other anti-CD20 therapy
- Multiple myeloma and chronic lymphocytic leukemia
