Background
- Oral JAK inhibitor
- Indications include COVID-19
Dosing
- 4 mg p.o. daily for 14 days, or until hospital discharge
Renal Dosing
- eGFR 30-60 mL/min: 2 mg p.o. daily
- eGFR 15-30 mL/min: 1 mg p.o. daily
Safety
Contraindications
- Contraindications and relative contraindications include hypersensitivity, co-existing infection, immunosuppression, increase liver enzymes.