Baricitinib

From IDWiki

Background

  • Oral JAK inhibitor
  • Indications include COVID-19

Dosing

  • 4 mg p.o. daily for 14 days, or until hospital discharge

Renal Dosing

  • eGFR 30-60 mL/min: 2 mg p.o. daily
  • eGFR 15-30 mL/min: 1 mg p.o. daily

Safety

Contraindications

  • Contraindications and relative contraindications include hypersensitivity, co-existing infection, immunosuppression, increase liver enzymes.