Chemotherapy

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Classes

  • Alkylating agents
    • Cyclophosphamide
    • Cisplatin
    • Temozolamide
  • Antimetabolites
    • 5-FU, capecitabine
    • Pemetrexed
  • Microtubule inhibitors
    • Vincristine
    • Taxanes
  • Anti-tumour antibiotics
    • Doxorubicin
    • Adreomycin
    • Bleomycin
  • Topoisomerase inhibitors
    • Topotecan

Side Effects

Chemotherapy Major side effects
Anthracyclines (adreomycin) Cardiotoxicity after a cumulative dose > 450
5-fluorouracil (5FU) Diarrhea
Capecitabine Hand-foot syndrome
Diarrhea
Cisplatin Nephrotoxicity
Taxanes Alopecia
Bleomycin Lung fibrosis
Vinca alkaloids Peripheral neuropathy