Chemotherapy

Classes

• Alkylating agents
  • Cyclophosphamide
  • Cisplatin
  • Temozolamide
• Antimetabolites
  • 5-fluorouracil, capecitabine
  • Pemetrexed
• Microtubule inhibitors
  • Vincristine
  • Taxanes
• Anti-tumour antibiotics
  • Doxorubicin
  • Adreomycin
  • Bleomycin
• Topoisomerase inhibitors
  • Topotecan

Side Effects

Chemotherapy	Major side effects
Anthracyclines (adreomycin)	Cardiotoxicity after a cumulative dose > 450
5-fluorouracil (5-FU)	Diarrhea
Capecitabine	Hand-foot syndrome Diarrhea
Cisplatin	Nephrotoxicity
Taxanes	Alopecia
Bleomycin	Lung fibrosis
Vinca alkaloids	Peripheral neuropathy