Sulfadiazine

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  • Antimicrobial that inhibits dihydrofolic acid synthesis
  • Indications include toxoplasmosis, malaria, and Nocardia
  • Adverse events include
    • GI intolerance
    • Pruritic rash
    • Bone marrow suppression of any line
    • Serum sickness and drug fever
    • Crystal-induced nephropathy
    • Photosensitivity
    • Hepatitis