Imipenem-cilastatin

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Revision as of 14:46, 14 November 2025 by Aidan (talk | contribs) (Created page with "== Background == * Broad-spectrum carbapenem * Spectrum includes enterococci and Acinetobacter ** Compared to meropenem, imipenem is more active against Acinetobacter and enterococci, and less active against Pseudomonas == Dosing == * Routine: 500 mg IV every 6 hours * Cystitis: 250-500 mg IV every 6 hours * Severe or pseudomonal infections: consider up to 1 g IV every 6 to 8 hours Category:Carbapenems")

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Background

Broad-spectrum carbapenem
Spectrum includes enterococci and Acinetobacter
- Compared to meropenem, imipenem is more active against Acinetobacter and enterococci, and less active against Pseudomonas

Dosing

Routine: 500 mg IV every 6 hours
Cystitis: 250-500 mg IV every 6 hours
Severe or pseudomonal infections: consider up to 1 g IV every 6 to 8 hours

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Carbapenems