Imipenem-cilastatin
From IDWiki
Background
- Broad-spectrum carbapenem
- Spectrum includes enterococci and Acinetobacter
- Compared to meropenem, imipenem is more active against Acinetobacter and enterococci, and possibly less active against Pseudomonas
Dosing
- Routine: 500 mg IV every 6 hours
- Cystitis: 250-500 mg IV every 6 hours
- Severe or pseudomonal infections: consider up to 1 g IV every 6 to 8 hours
