Background
- Originally developed to predict mortality with Pseudomonas aeruginosa bacteremia
- Now used more broadly for mortality from infections more generally
- A modified Pitt bacteremia score (mPBS) also exists[1]
Components
- Measured at onset of bacteremia
| Criterion | Points (original) | Points (modified) |
|---|---|---|
| Fever (°C) | ||
| ≤35 or ≥40 | 2 | |
| 35.1-36.0 or 39.0-39.9 | 1 | |
| 36.1-38.9 | 0 | |
| Hypotension: drop by >30 SBP or >20 DBP, or vasopressors, or SBP <90 | 2 | 2 |
| Mechanical ventilation | 2 | 2 |
| Cardiac arrest | 4 | 4 |
| Mental status | ||
| Alert | 0 | 0 |
| Disoriented | 1 | 1 |
| Stuporous/comatose | 2 | 2 |
| Comatose | 4 | 4 |
| Dialysis | 2 | |
Interpretation
- ≥4 usually used as a cutoff for increased risk of death
| Score | Gram-negative bacteremia (28-day mortality)[2] | SAB (30-day mortality)[3] | Nonbacteremic infections (14-day mortality)[4] | Candidemia (mPBS) (30-day mortality)[1] |
|---|---|---|---|---|
| 0 | ≤1% | 8% | 5% | 14% |
| 1 | 1% | 5% | ||
| 2 | 1.5% | 15% | ||
| 3 | 2% | 40% | ||
| 4 | 3% | 47% | 40% | 37% |
| 5 | 5% | 33% | ||
| 6 | 7% | 43% | ||
| 7 | 10% | 75% | ||
| 8 | 14% | 69% | ||
| 9 | 20% | |||
| ≥10 | 27-81% |
- ↑ 1.0 1.1 Nakada-Motokawa, N, Miyazaki, T, Ueda, T, et al. Modified Pitt bacteremia score for predicting mortality in patients with candidaemia: A multicentre seven-year retrospective study conducted in Japan. Mycoses. 2021; 64: 1498-1507. https://doi.org/10.1111/myc.13380
- ↑ Al-Hasan MN, Lahr BD, Eckel-Passow JE, Baddour LM. Predictive scoring model of mortality in Gram-negative bloodstream infection. Clin Microbiol Infect. 2013 Oct;19(10):948-54. doi: 10.1111/1469-0691.12085. Epub 2012 Nov 27. PMID: 23190091.
- ↑ Roth JA, Tschudin-Sutter S, Dangel M, Frei R, Battegay M, Widmer AF. Value of the Pitt Bacteraemia Score to predict short-term mortality in Staphylococcus aureus bloodstream infection: a validation study. Swiss Med Wkly [Internet]. 2017 Aug. 10 [cited 2023 Feb. 8];147(3132):w14482. Available from: https://smw.ch/index.php/smw/article/view/2342
- ↑ Heather Henderson, Courtney L Luterbach, Eric Cober, Sandra S Richter, Robert A Salata, Robert C Kalayjian, Richard R Watkins, Yohei Doi, Keith S Kaye, Scott Evans, Vance G Fowler, Jr, Robert A Bonomo, Anthony Harris, Sonia Napravnik, David Van Duin, The Pitt Bacteremia Score Predicts Mortality in Nonbacteremic Infections, Clinical Infectious Diseases, Volume 70, Issue 9, 1 May 2020, Pages 1826–1833, https://doi.org/10.1093/cid/ciz528
References
- a b Nana Nakada‐Motokawa, Taiga Miyazaki, Takashi Ueda, Yuka Yamagishi, Koichi Yamada, Hideki Kawamura, Hiroshi Kakeya, Hiroshi Mukae, Hiroshige Mikamo, Yoshio Takesue, Shigeru Kohno. Modified Pitt bacteremia score for predicting mortality in patients with candidaemia: A multicentre seven‐year retrospective study conducted in Japan. Mycoses. 2021;64(12):1498-1507. doi:10.1111/myc.13380.
- ^ M.N. Al-Hasan, B.D. Lahr, J.E. Eckel-Passow, L.M. Baddour. Predictive scoring model of mortality in Gram-negative bloodstream infection. Clinical Microbiology and Infection. 2013;19(10):948-954. doi:10.1111/1469-0691.12085.
- ^ 10.4414/smw.2017.14482
- ^ Heather Henderson, Courtney L Luterbach, Eric Cober, Sandra S Richter, Robert A Salata, Robert C Kalayjian, Richard R Watkins, Yohei Doi, Keith S Kaye, Scott Evans, Vance G Fowler, Robert A Bonomo, Anthony Harris, Sonia Napravnik, David Van Duin. The Pitt Bacteremia Score Predicts Mortality in Nonbacteremic Infections. Clinical Infectious Diseases. 2019;70(9):1826-1833. doi:10.1093/cid/ciz528.
