Spontaneous gram-negative meningitis
From IDWiki
Background
Microbiology
- Most commonly caused by Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Acinetobacter
- Also Citrobacter, Serratia marcescens, Enterobacter, and Proteus mirabilis
Risk Factors
- Diabetes mellitus
- Cirrhosis
- End-stage renal disease
- Substance abuse, including alcohol use disorder
- Cancer
Clinical Presentation
- As per other forms of bacterial meningitis
Management
- CNS dosed antibiotics to complete 21 days is typically sufficient
