Massive splenomegaly

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Differential Diagnosis

  • Myeloproliferative disorders (hard spleen)
  • Leishmaniasis (soft spleen)
  • Schistosomiasis (from portal hypertension)
  • Tropical splenomegaly syndrome (from Plasmodium infection)
  • Non-massive splenomegaly
    • Typhoid
    • Brucellosis