Clostridium septicum

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Clostridium septicum /
Revision as of 21:18, 13 April 2020 by Aidan (talk | contribs)

Background

Microbiology

Risk factors

  • Associated with colon cancer or neutropenia
  • Diabetes also a risk factor

Clinical Presentation

  • Can cause bacteremia and non-traumatic myonecrosis
  • Clinical presentation is typically fulminant sepsis, which very high mortality

Management

  • Aggressive surgical debridement, possibly including amputation
  • Broad-spectrum antibiotics for necrotizing fasciitis are indicated until the microbiologic diagnosis is confirmed
  • First-line antimicrobials are penicillin plus clindamycin