Pseudomonas aeruginosa
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Pseudomonas aeruginosa /
Revision as of 03:38, 15 August 2019 by Aidan (talk | contribs) (Aidan moved page Pseudomonas to Pseudomonas aeruginosa without leaving a redirect)
Pseudomonas aeruginosa
Microbiology
- Oxidase-positive, non-fermenting Gram negative bacillus
Mechanisms of Resistance
- Broad intrinsic and acquired antibiotic resistance
- Membrane impermeability
- MexAB-OprM efflux pump
- Acquired mutations
- Inducible AmpC β-lactamase
- Plasmid sharing
Environment and Infections
- Loves moist and wet environments
- Causes healthcare-associated infections
- UTI, SSI, bacteremia, HAP, VAP
- Especially common in cystic fibrosis
Treatment
- See [Antipseudomonal antibiotics](/Infectious Diseases/Basics/Antimicrobials/Antipseudomonal antibiotics.md)
- Double coverage (ß-lactam + non-ß-lactam) in cases of severe infection in order to ensure activity against the infection
