Mostly transmitted by mosquitoes (mainly Aedes aegypti), but can be sexually transmitted
Present in most of South and Central America including the Caribbean, sub-Saharan Africa, the Indian subcontinent, southeast Asia, and the Pacific islands
Transmission
Detectable in serum of pregnant women for 10 weeks after symptom onset
Detectable in semen for up to 188 days after symptom onset (but only 69 days for replication-competent virus)
Longest documented duration from symptom onset to sexual transmission is 32 to 41 days
Trimester
Any Microcephaly
Congenital Zika Syndrome
first
10%
7%
second
3%
1%
third
4%
1%
overall
6%
3%
Clinical Manifestations
Cranial morphology due to a disruption in the fetal brain sequence