Betacoronavirus pandemicum

Background

Microbiology

• Coronavirus related to SARS-CoV

Epidemiology

• First cases detected Dec 2019 related to likely exposure in wet market in Wuhan, Hubei, China
• Declared pandemic by WHO in 2020

Clinical Manifestations

• Incubation period 4-5 days on average, possibly as long as 14 days in some cases
• Main presenting symptoms were fever and cough
• Other symptoms include dyspnea, rhinorrhea, vomiting, diarrhea

Management

• Primarily supportive
• Investigational therapeutics include tocilizumab, lopinavir/ritonavir, and chloroquine