Enterococcus bacteremia

DENOVA Score

• Berge A, Krantz A, Östlund H, Nauclér P, Rasmussen M. The DENOVA score efficiently identifies patients with monomicrobial Enterococcus faecalis bacteremia where echocardiography is not necessary. Infection. 2019 Feb;47(1):45-50.
• Determines need for echocardiography
• Components:
  • Duration of symptoms (≥7 days)
  • Embolization (clinical or radiographic)
  • Number of positive cultures ≥2
  • Origin of infection unknown
  • Valve disease: native valve disease, previous IE, or the presence of a valve prosthesis
  • Auscultation of murmur (any)
• A cutoff of ≥3 had sensitivity of 100% and specificity of 85% for endocarditis