Enterococcus bacteremia
From IDWiki
Enterococcus bacteremia
Background
- Bacteremia caused by an Enterococcus
- Risk of infective endocarditis of about 17% for Enterococcus faecalis1
Management
DENOVA Score
- Determines need for echocardiography2
- Criteria:
- Duration of symptoms (≥7 days)
- Embolization (clinical or radiographic)
- Number of positive cultures ≥2
- Origin of infection unknown
- Valve disease: native valve disease, previous IE, or the presence of a valve prosthesis
- Auscultation of murmur (any)
- A cutoff of ≥3 had sensitivity of 100% and specificity of 85% for endocarditis
References
- ^ Lauge Østergaard, Niels Eske Bruun, Marianne Voldstedlund, Magnus Arpi, Christian Østergaard Andersen, Henrik C Schønheyder, Lars Lemming, Flemming Rosenvinge, Nana Valeur, Peter Søgaard, Paal Skytt Andersen, Robert Skov, Ming Chen, Kasper Iversen, Sabine Gill, Trine Kiilerich Lauridsen, Anders Dahl, Louise Bruun Oestergaard, Jonas Agerlund Povlsen, Claus Moser, Henning Bundgaard, Lars Køber, Emil Loldrup Fosbøl. Prevalence of infective endocarditis in patients with positive blood cultures: a Danish nationwide study. European Heart Journal. 2019;40(39):3237-3244. doi:10.1093/eurheartj/ehz327.
- ^ Andreas Berge, Andrea Krantz, Helena Östlund, Pontus Nauclér, Magnus Rasmussen. The DENOVA score efficiently identifies patients with monomicrobial Enterococcus faecalis bacteremia where echocardiography is not necessary. Infection. 2018;47(1):45-50. doi:10.1007/s15010-018-1208-3.
