Background
- Originally developed to predict mortality with Pseudomonas aeruginosa bacteremia
- Now used more broadly for mortality from infections more generally
- A modified Pitt bacteremia score (mPBS) also exists[1]
Components
- Measured at onset of bacteremia
| Criterion | Points (original) | Points (modified) |
|---|---|---|
| Fever (°C) | ||
| ≤35 or ≥40 | 2 | |
| 35.1-36.0 or 39.0-39.9 | 1 | |
| 36.1-38.9 | 0 | |
| Hypotension: drop by >30 SBP or >20 DBP, or vasopressors, or SBP <90 | 2 | 2 |
| Mechanical ventilation | 2 | 2 |
| Cardiac arrest | 4 | 4 |
| Mental status | ||
| Alert | 0 | 0 |
| Disoriented | 1 | 1 |
| Stuporous/comatose | 2 | 2 |
| Comatose | 4 | 4 |
| Dialysis | 2 | |
Interpretation
- ≥4 usually used as a cutoff for increased risk of death
| Score | Gram-negative bacteremia (28-day mortality)[2] | SAB (30-day mortality)[3] | Nonbacteremic infections (14-day mortality)[4] | Candidemia (mPBS) (30-day mortality)[1] |
|---|---|---|---|---|
| 0 | ≤1% | 8% | 5% | 14% |
| 1 | 1% | 5% | ||
| 2 | 1.5% | 15% | ||
| 3 | 2% | 40% | ||
| 4 | 3% | 47% | 40% | 37% |
| 5 | 5% | 33% | ||
| 6 | 7% | 43% | ||
| 7 | 10% | 75% | ||
| 8 | 14% | 69% | ||
| 9 | 20% | |||
| ≥10 | 27-81% |
- ↑ 1.0 1.1 Nakada-Motokawa, N, Miyazaki, T, Ueda, T, et al. Modified Pitt bacteremia score for predicting mortality in patients with candidaemia: A multicentre seven-year retrospective study conducted in Japan. Mycoses. 2021; 64: 1498-1507. https://doi.org/10.1111/myc.13380
- ↑ Al-Hasan MN, Lahr BD, Eckel-Passow JE, Baddour LM. Predictive scoring model of mortality in Gram-negative bloodstream infection. Clin Microbiol Infect. 2013 Oct;19(10):948-54. doi: 10.1111/1469-0691.12085. Epub 2012 Nov 27. PMID: 23190091.
- ↑ Roth JA, Tschudin-Sutter S, Dangel M, Frei R, Battegay M, Widmer AF. Value of the Pitt Bacteraemia Score to predict short-term mortality in Staphylococcus aureus bloodstream infection: a validation study. Swiss Med Wkly [Internet]. 2017 Aug. 10 [cited 2023 Feb. 8];147(3132):w14482. Available from: https://smw.ch/index.php/smw/article/view/2342
- ↑ Heather Henderson, Courtney L Luterbach, Eric Cober, Sandra S Richter, Robert A Salata, Robert C Kalayjian, Richard R Watkins, Yohei Doi, Keith S Kaye, Scott Evans, Vance G Fowler, Jr, Robert A Bonomo, Anthony Harris, Sonia Napravnik, David Van Duin, The Pitt Bacteremia Score Predicts Mortality in Nonbacteremic Infections, Clinical Infectious Diseases, Volume 70, Issue 9, 1 May 2020, Pages 1826–1833, https://doi.org/10.1093/cid/ciz528
