Enterococcus: Difference between revisions

From IDWiki
Enterococcus
()
m (Text replacement - "[[Cellular shape::" to "[[Shape::")
Line 4: Line 4:
===Microbiology===
===Microbiology===


*Genus of facultative anaerobic, non-spore-forming, [[Hemolysis pattern::α-hemolytic|alpha-]] or [[Hemolysis pattern::γ-hemolytic|gamma-hemolytic]], catalase [[Catalase::negative]], [[Stain::Gram-positive]] [[Cellular shape::coccus|cocci]]
*Genus of facultative anaerobic, non-spore-forming, [[Hemolysis pattern::α-hemolytic|alpha-]] or [[Hemolysis pattern::γ-hemolytic|gamma-hemolytic]], catalase [[Catalase::negative]], [[Stain::Gram-positive]] [[Shape::coccus|cocci]]
*Grows on bile esculin agar
*Grows on bile esculin agar
*[[PYR test|PYR]] positive
*[[PYR test|PYR]] positive

Revision as of 15:16, 8 October 2020

Background

Microbiology

  • Genus of facultative anaerobic, non-spore-forming, alpha- or gamma-hemolytic, catalase negative, Gram-positive cocci
  • Grows on bile esculin agar
  • PYR positive
  • Most are Lancefield group D
  • Commensal gut flora
  • Increasing antibiotic resistance

Species

  • E. faecalis
    • More common (90-95%)
    • More commonly genitourinary source
    • More susceptible to antibiotics
  • E. faecium
    • Less common (5-10%)
    • More commonly gastrointestinal source
    • Less susceptible to antibiotics
    • Most common VRE
  • E. gallinarum
  • E. casseliflavus

Vacomycin Resistance

  • Vancomycin binds to d-Ala-d-Ala pentapeptids, interfering with cell wall synthesis
  • VanA: most common. Mutation to d-Ala-d-Lac, leading to high resistance to glycopeptides.
  • VanB: more common in E. faecium in Australia
  • VanC: chromosomal resistance on E. gallinarum and E. casseliflavus

Management

VRE