Uveitis: Difference between revisions

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==Background==
==Background==

* Inflammation of the uvea, which comprises the iris, ciliary body, and choroid, or of the retina
*Inflammation of the uvea, which comprises the iris, ciliary body, and choroid, or of the retina
** Anterior: iritis, iridocyclitis
**Anterior: iritis, iridocyclitis
** Intermediate: pars planitis
**Intermediate: pars planitis
** Posterior: choroiditis, retinitis, chorioretinitis
**Posterior: choroiditis, retinitis, chorioretinitis
** Panuveitis
**Panuveitis


==Differential Diagnosis==
==Differential Diagnosis==
===Infectious causes===
===Infectious causes===

* Anterior uveitis (10% infectious)
** [[Herpes simplex virus]] (by far the most common infectious cause)
*Anterior uveitis (10% infectious)
**[[Herpes simplex virus]] (by far the most common infectious cause)
** [[Varicella-zoster virus]]
** [[Syphilis]]
**[[Varicella-zoster virus]]
** [[Tuberculosis]]
**[[Syphilis]]
** [[Lyme disease]]
**[[Tuberculosis]]
** [[Leprosy]]
**[[Lyme disease]]
**[[Leprosy]]
* Intermediate uveitis (rarely infectious)
*Intermediate uveitis (rarely infectious)
** [[Lyme disease]]
**[[Lyme disease]]
* Posterior uveitis (50% infectious)
*Posterior uveitis (50% infectious)
** [[Toxoplasmosis]]
**[[Toxoplasmosis]]
** [[Acute retinal necrosis]] from [[HSV]], [[VZV]], and [[CMV]]
**[[Acute retinal necrosis]] from [[HSV]], [[VZV]], and [[CMV]]
** [[CMV]] retinitis, in immunocompromised patients
**[[CMV]] retinitis, in immunocompromised patients
** [[Toxocara]]
** [[Syphilis]]
**[[Toxocara]]
** [[Cat-scratch disease]]
**[[Syphilis]]
**[[Cat-scratch disease]]
** [[Candida]] endophthalmitis
**[[Candida]] endophthalmitis
** [[West Nile virus]], causing a multifocal chorioretinitis
**[[West Nile virus]], causing a multifocal chorioretinitis
* Panuveitis
*Panuveitis
** [[Syphilis]]
** [[Tuberculosis]]
**[[Syphilis]]
**[[Tuberculosis]]
** [[Candida]] endophthalmitis
**[[Candida]] endophthalmitis
** [[Leptospirosis]], without retinal or choroidal lesions
**[[Leptospirosis]], without retinal or choroidal lesions
* Other
*Other
** [[Brucella]], causing a chronic relapsing uveitis that is typically posterior but can be anterior or panuveitis[[CiteRef::rolando2008oc]]
**[[Brucella]], causing a chronic relapsing uveitis that is typically posterior but can be anterior or panuveitis[[CiteRef::rolando2008oc]]
** [[Chikungunya]]
** [[Ebola virus]]
**[[Chikungunya]]
** [[Zika virus]]
**[[Ebola virus]]
**[[Zika virus]]

== Clinical Manifestations ==

* Anterior: painful red eye and vision loss
* Intermediate: vision loss with floaters, usually painless (and rarely infectious)
* Posterior: painless vision loss


[[Category:Ophthalmology]]
[[Category:Ophthalmology]]
[[Category:Infectious diseases]]
[[Category:Eye infections]]

Latest revision as of 14:38, 12 August 2020

Background

  • Inflammation of the uvea, which comprises the iris, ciliary body, and choroid, or of the retina
    • Anterior: iritis, iridocyclitis
    • Intermediate: pars planitis
    • Posterior: choroiditis, retinitis, chorioretinitis
    • Panuveitis

Differential Diagnosis

Infectious causes

Clinical Manifestations

  • Anterior: painful red eye and vision loss
  • Intermediate: vision loss with floaters, usually painless (and rarely infectious)
  • Posterior: painless vision loss

References

  1. ^  Isaias Rolando, Liset Olarte, Gustavo Vilchez, Marina Lluncor, Larissa Otero, Mark Paris, Carlos Carrillo, Eduardo Gotuzzo. Ocular Manifestations Associated with Brucellosis: A 26‐Year Experience in Peru. Clinical Infectious Diseases. 2008;46(9):1338-1345. doi:10.1086/529442.