Kawasaki disease: Difference between revisions

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== Diagnostic Criteria ==
==Diagnostic Criteria==


*"Warm CREAM" mnemonic: fever plus conjunctivitis, rash, extremity involvement, adenopathy, and mucosal involvement
* "Warm CREAM"
* Fever persisting at least 5 d - Presence of at least 4 principal features:
*Fever persisting at least 5 d - Presence of at least 4 principal features:
** Changes in extremities
**Changes in extremities
*** Acute: Erythema of palms, soles; edema of hands, feet
***Acute: Erythema of palms, soles; edema of hands, feet
*** Subacute: Periungual peeling of fingers, toes in weeks 2 and 3
***Subacute: Periungual peeling of fingers, toes in weeks 2 and 3
** Polymorphous exanthem
**Polymorphous exanthem
** Bilateral bulbar conjunctival injection without exudate
**Bilateral bulbar conjunctival injection without exudate
** Changes in lips and oral cavity: Erythema, lips cracking, strawberry tongue, diffuse injection of oral and pharyngeal mucosae
**Changes in lips and oral cavity: Erythema, lips cracking, strawberry tongue, diffuse injection of oral and pharyngeal mucosae
** Cervical lymphadenopathy (>1.5-cm diameter), usually unilateral
**Cervical lymphadenopathy (>1.5-cm diameter), usually unilateral
* Exclusion of other diseases with similar findings‡
*Exclusion of other diseases with similar findings‡


=== Incomplete Kawasaki disease ===
===Incomplete Kawasaki disease===


* Do not meet the full criteria above
*Do not meet the full criteria above


== Differential Diagnosis ==
==Differential Diagnosis==


* Viral infections: measles, adenovirus, enterovirus, Epstein-Barr virus (EBV)
*Viral infections: [[measles]], [[adenovirus]], [[enterovirus]], [[Epstein-Barr virus]]
* Scarlet fever
*[[Scarlet fever]]
* Staphylococcal scalded skin syndrome
*[[Staphylococcal scalded skin syndrome]]
* Toxic shock syndrome
*[[Toxic shock syndrome]]
* Bacterial cervical lymphadenitis
*Bacterial cervical lymphadenitis
* Drug hypersensitivity reactions
*Drug hypersensitivity reactions
* Stevens-Johnson syndrome
*[[Stevens-Johnson syndrome]]
* Juvenile rheumatoid arthritis
*[[Juvenile rheumatoid arthritis]]
* Rocky Mountain spotted fever
*[[Rocky Mountain spotted fever]]
* Leptospirosis
*[[Leptospirosis]]
* Mercury hypersensitivity reaction (acrodynia)
*Mercury hypersensitivity reaction (acrodynia)


[[Category:Pediatrics]]
[[Category:Pediatrics]]

Revision as of 15:37, 30 July 2020

Diagnostic Criteria

  • "Warm CREAM" mnemonic: fever plus conjunctivitis, rash, extremity involvement, adenopathy, and mucosal involvement
  • Fever persisting at least 5 d - Presence of at least 4 principal features:
    • Changes in extremities
      • Acute: Erythema of palms, soles; edema of hands, feet
      • Subacute: Periungual peeling of fingers, toes in weeks 2 and 3
    • Polymorphous exanthem
    • Bilateral bulbar conjunctival injection without exudate
    • Changes in lips and oral cavity: Erythema, lips cracking, strawberry tongue, diffuse injection of oral and pharyngeal mucosae
    • Cervical lymphadenopathy (>1.5-cm diameter), usually unilateral
  • Exclusion of other diseases with similar findings‡

Incomplete Kawasaki disease

  • Do not meet the full criteria above

Differential Diagnosis

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