Guillain-Barré syndrome: Difference between revisions

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== Etiology ==
== Background ==

* ''[[Campylobacter jejuni]]''
* Causes either acute inflammatory demyelinating polyneuropathy, or acute motor axonal neuropathy, or acute motor and sensory axonal neuropathy
* [[Cytomegalovirus]]

* [[Epstein-Barr virus]]
===Etiology===
* [[Zika virus]]

* [[HIV]]
*''[[Campylobacter jejuni]]''
* Non-infectious causes, including imunization, surgery, trauma, and hematopoietic stem cell transplantation
*[[Cytomegalovirus]]
*[[Epstein-Barr virus]]
*[[Zika virus]]
*[[HIV]]
*Non-infectious causes, including immunization, surgery, trauma, and hematopoietic stem cell transplantation

=== Epidemiology ===

* About 1 case per 100,000 people per year in Western countries

== Clinical Manifestations ==

* Ascending paralysis ± sensory involvement
* Usually occurs 1 to 2 weeks after an immune-stimulating even such as illness or vaccination
** Preceding illness usually a gastrointestinal or respiratory infection
** [[Campylobacter jejuni]] is the most common causative organism identified
** Rare following influenza vaccination; most notable was the 1976 H1N1 vaccine, with about 1 in 100,000 vaccine recipients developing GBS

== Further Reading ==

* Guillain-Barré syndrome. ''Lancet''. 2016;388:717-727. doi: [https://doi.org/10.1016/S0140-6736(16)00339-1 10.1016/S0140-6736(16)00339-1]

[[Category:Neurology]]
[[Category:Infectious diseases]]

Revision as of 01:42, 14 July 2020

Background

  • Causes either acute inflammatory demyelinating polyneuropathy, or acute motor axonal neuropathy, or acute motor and sensory axonal neuropathy

Etiology

Epidemiology

  • About 1 case per 100,000 people per year in Western countries

Clinical Manifestations

  • Ascending paralysis ± sensory involvement
  • Usually occurs 1 to 2 weeks after an immune-stimulating even such as illness or vaccination
    • Preceding illness usually a gastrointestinal or respiratory infection
    • Campylobacter jejuni is the most common causative organism identified
    • Rare following influenza vaccination; most notable was the 1976 H1N1 vaccine, with about 1 in 100,000 vaccine recipients developing GBS

Further Reading