Clostridium septicum: Difference between revisions
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Clostridium septicum
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== Background == |
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=== Microbiology === |
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* [[Has Gram stain::Gram-positive]] [[Has shape::bacillus]] |
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* Member of the genus ''[[Clostridium species|Clostridium]]'' |
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* Produces alpha toxin |
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=== Risk factors === |
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* Diabetes also a risk factor |
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== Clinical Presentation == |
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* Can cause bacteremia and non-traumatic myonecrosis |
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* Clinical presentation is typically fulminant sepsis, which very high mortality |
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== Management == |
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* Aggressive surgical debridement, possibly including amputation |
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* Broad-spectrum antibiotics for [[necrotizing fasciitis]] are indicated until the microbiologic diagnosis is confirmed |
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* First-line antimicrobials are [[Is treated by::penicillin]] plus [[Is treated by::clindamycin]] |
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{{DISPLAYTITLE:''Clostridium septicum''}} |
{{DISPLAYTITLE:''Clostridium septicum''}} |
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Revision as of 21:18, 13 April 2020
Background
Microbiology
- Gram-positive bacillus
- Member of the genus Clostridium
- Produces alpha toxin
Risk factors
- Associated with colon cancer or neutropenia
- Diabetes also a risk factor
Clinical Presentation
- Can cause bacteremia and non-traumatic myonecrosis
- Clinical presentation is typically fulminant sepsis, which very high mortality
Management
- Aggressive surgical debridement, possibly including amputation
- Broad-spectrum antibiotics for necrotizing fasciitis are indicated until the microbiologic diagnosis is confirmed
- First-line antimicrobials are penicillin plus clindamycin
