Neisseria gonorrhoeae: Difference between revisions

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Neisseria gonorrhoeae
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** About 50% resistance to [[fluoroquinolones]]
** About 50% resistance to [[fluoroquinolones]]
** Rates of MDR gonorrhea is increasing in Canada, mostly driven by [[azithromycin]] resistance
** Rates of MDR gonorrhea is increasing in Canada, mostly driven by [[azithromycin]] resistance
** XDR gonorrhea is still rare in Canada [[CiteRef::martin2019mu]]
** XDR gonorrhea is still rare in Canada <ref>{{cite journal|title=Multidrug-resistant and extensively drug-resistant gonorrhea in Canada, 2012–2016|journal=CCDR|year=2019|volume=45|issue=2/3|pages=45–53|doi=10.14745/ccdr.v45i23a01}}</ref>


== Clinical Presentation ==
== Clinical Presentation ==

Revision as of 02:41, 28 August 2019

  • Causes gonorrhea

Epidemiology

  • Resistance
    • About 50% resistance to fluoroquinolones
    • Rates of MDR gonorrhea is increasing in Canada, mostly driven by azithromycin resistance
    • XDR gonorrhea is still rare in Canada 1

Clinical Presentation

Anorectal gonorrhea

  • Often asymptomatic
  • Can cause anorectal pain, discharge, and pruritis
  • Anal intercourse not required, especially in women

Disseminated gonococcal infection

  • Classically presents with tenosynovitis (often of wrists) or frank arthritis, with pustular lesions
  • Diagnosed with genital testing for gonorrhea, ± blood cultures or arthrocentesis

Diagnosis

  • Resistance
    • MDR gonorrhea: resistance to one of azithromycin or a cephalosporin
    • XDR if resistance to both azithromycin and a cephalosporin

References

References

  1. ^  I Martin, P Sawatzky, V Allen, B Lefebvre, LMN Hoang, P Naidu, J Minion, P Van Caeseele, D Haldane, RR Gad, G Zahariadis, A Corriveau, G German, K Tomas, MR Mulvey. Multidrug-resistant and extensively drug-resistant Neisseria gonorrhoeae in Canada, 2012–2016. Canada Communicable Disease Report. 2019;45(2/3):45-53. doi:10.14745/ccdr.v45i23a01.