Ecthyma gangrenosum: Difference between revisions
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===Microbiology=== |
===Microbiology=== |
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*[[Pseudomonas aeruginosa]] the most common cause (75%)[[CiteRef::vaiman2014ec]] |
*'''[[Pseudomonas aeruginosa]] is by far the most common cause''' (75%)[[CiteRef::vaiman2014ec]] |
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**Likely the only cause in immunocompetent patients[[CiteRef::2015ec]] |
**Likely the only cause in immunocompetent patients[[CiteRef::2015ec]] |
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*Other bacteria (15%) |
*Other bacteria (15%) |
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**[[Scytalidium dimidiatum]] |
**[[Scytalidium dimidiatum]] |
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**[[Metarhizium anisopliae]] |
**[[Metarhizium anisopliae]] |
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== Clinical Manifestations == |
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* Almost exclusively in immunocompromised patients with pseudomonal bacteremia |
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* Presents with gray macule or papule with surrounding erythema followed by progression to necrosis with black ulceration and eschar with erythematous halo |
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[[Category:Skin and soft tissue infections]] |
[[Category:Skin and soft tissue infections]] |
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Latest revision as of 01:53, 25 February 2026
Background
- Necrotizing skin ulcers secondary to bacteremia in immunocompromised patients, traditionally caused by Pseudomonas aeruginosa
Microbiology
- Pseudomonas aeruginosa is by far the most common cause (75%)1
- Likely the only cause in immunocompetent patients2
- Other bacteria (15%)
- Fungi (10%)
- Fusarium solani, likely the most common fungal cause
- Candida albicans
- Candida tropicalis
- Mucor pusillus
- Scytalidium dimidiatum
- Metarhizium anisopliae
Clinical Manifestations
- Almost exclusively in immunocompromised patients with pseudomonal bacteremia
- Presents with gray macule or papule with surrounding erythema followed by progression to necrosis with black ulceration and eschar with erythematous halo
References
- ^ M. Vaiman, T. Lazarovitch, L. Heller, G. Lotan. Ecthyma gangrenosum and ecthyma-like lesions: review article. European Journal of Clinical Microbiology & Infectious Diseases. 2014;34(4):633-639. doi:10.1007/s10096-014-2277-6.
- ^ Michael Vaiman;Tsilia Lasarovitch;Lior Heller;Gad Lotan. Ecthyma gangrenosum versus ecthyma-like lesions: should we separate these conditions?. Acta Dermatovenerologica Alpina Pannonica et Adriatica. 2015;24(4). doi:10.15570/actaapa.2015.18.