Smudge cells: Difference between revisions

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== Differential Diagnosis ==
== Differential Diagnosis ==
* Classically associated with [[CLL]], where they represent ruptured diseased B cells
* Classically associated with [[CLL]], where they represent ruptured diseased B cells
* May also be seen in some infections (including [[infectious mononucleosis]]), post-cardiac arrest, inflammatory conditions, and as an artefact
* May also be seen in some infections (including [[infectious mononucleosis]]), post-cardiac arrest, inflammatory conditions
** Also solid-organ malignancies and artifact


[[Category:Hematology]]
[[Category:Hematology]]

Latest revision as of 20:04, 14 February 2025

Background

  • Also called basket cells or Gumprecht shadows
  • Remnants of fragile leukocytes that are smeared during preparation of a blood film

Differential Diagnosis

  • Classically associated with CLL, where they represent ruptured diseased B cells
  • May also be seen in some infections (including infectious mononucleosis), post-cardiac arrest, inflammatory conditions
    • Also solid-organ malignancies and artifact