Waterhouse-Friderichsen syndrome: Difference between revisions
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* Infectious |
* Infectious |
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** [[Neisseria meningitidis]] (most common) |
** '''[[Neisseria meningitidis]] (most common)''' |
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** [[Pseudomonas aeruginosa]] |
** [[Pseudomonas aeruginosa]] |
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** [[Streptococcus pneumoniae]] |
** [[Streptococcus pneumoniae]] and other [[streptococci]] |
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** [[Haemophilus influenzae]] |
** [[Haemophilus influenzae]] |
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** [[Staphylococcus]] |
** [[Staphylococcus aureus]] |
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** Many others, in case reports, including viral causes |
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* Non-infectious |
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* Non-infectious risk factors include: anticoagulation, [[thrombocytopenia]], [[Heparin-induced thrombocytopenia|HIT]], [[Antiphospholipid antibody syndrome|APLA]], '''trauma''', postoperative |
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=== Epidemiology === |
=== Epidemiology === |
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Latest revision as of 16:15, 5 February 2026
Background
Etiology
- Infectious
- Neisseria meningitidis (most common)
- Pseudomonas aeruginosa
- Streptococcus pneumoniae and other streptococci
- Haemophilus influenzae
- Staphylococcus aureus
- Many others, in case reports, including viral causes
- Non-infectious risk factors include: anticoagulation, thrombocytopenia, HIT, APLA, trauma, postoperative
Epidemiology
- More common in children, but can happen at any age
Clinical Manifestations
- Shock
- Widespread purpura secondary to disseminated intravascular coagulation
- Rapidly-developing adrenal insufficiency from bilateral adrenal hemorrhage
