Opioid use disorder: Difference between revisions
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*[[Methadone]] second-line |
*[[Methadone]] second-line |
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*Slow-release opioids such as [[Kadian]] third-line |
*Slow-release opioids such as [[Kadian]] third-line |
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== Prevention == |
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* Follow safe prescribing practices |
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* Risk assessment |
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** Consider their personal and family history of psychiatric illness and substance use disorder |
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** Consider their social history, including their living situation, safety of housing, personal safety, children or dependents, and social supports |
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** Can use tools such as the [[opioid risk tool]] or [[SOAPP-R]] as a more formal risk assessment |
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==Further Reading== |
==Further Reading== |
Revision as of 19:24, 9 July 2020
Background
- A substance use disorder involving heroin, fentanyl, or other opioid medications
Epidemiology
- The risk of OUD among patients treated with opioids for chronic pain is around 8 to 30%
Management
- Precipitated withdrawal more dangerous than natural withdrawal
Acute Overdose
- First give boluses of naloxone 0.04mg to 0.08mg IV to improve respiratory depression escalated quickly q2-3 minutes up to 0.4, 2, 4, 10, 15mg (start low and go fast)
- Then start infusion of 2/3 the effective dose per hour
- QRS and QT lengthening by blocking Na and K channels
- May need repeated defibrillation, overdrive pacing, or ECMO
Opioid Substitution Therapy (OST)
Prevention
- Follow safe prescribing practices
- Risk assessment
- Consider their personal and family history of psychiatric illness and substance use disorder
- Consider their social history, including their living situation, safety of housing, personal safety, children or dependents, and social supports
- Can use tools such as the opioid risk tool or SOAPP-R as a more formal risk assessment
Further Reading
- Management of opioid use disorders: a national clinical practice guideline. CMAJ. 2018;190(9):e247-e257. doi: 10.1503/cmaj.170958