Dyspepsia

Etiology

• Functional dyspepsia (75%)
• Organic cause (25%)
  • PUD, GERD, NSAIDs, malignancy

Clinical Manifestations

• Postprandial distress: fullness, early satiety
• Epigastric pain dyndrome: pain or burning
• Alarm features:
  • Family history of upper GI cancer
  • Weight loss
  • GI bleed
  • Dysphagia or odynophagia
  • Iron-deficiency anemia
  • Lymphadenopthay
  • Mass on exam
  • Jaundice

Investigations

• Lab
  • Helicobacter pylori serology, to rule out infection
    • Urea breath test
    • Stool antigen test
• Other
  • EGD
    • First-line if they are older or have alarm symptoms

Management

• Hold NSAIDs, if they are on it