Powassan virus: Difference between revisions
From IDWiki
No edit summary |
No edit summary |
||
| Line 6: | Line 6: | ||
=== Microbiology === |
=== Microbiology === |
||
* Single-stranded positive-sense RNA virus in the genus ''Flavivirus'', family [[Flaviviridae]] |
* Single-stranded positive-sense RNA virus in the genus ''Flavivirus'', family [[Flaviviridae]] |
||
* Two genotypes: lineage 1 and lineage 2 |
|||
=== Epidemiology === |
|||
* Transmitted by a number of ''Ixodes'' and ''Dermacentor'' ticks |
|||
** ''[[Ixodes cookei]]'', ''[[Ixodes scapularis]]'', ''[[Ixodes marxi]]'', ''[[Ixodes spinipalpus]]'', ''[[Dermacentor andersoni]]'', and ''[[Dermacentor variabilis]]'' |
|||
== Presentation == |
|||
* Incubation period 1 to 3 weeks |
|||
* Fever, headache, confusion, weakness, encephalopathy, focal neurological deficits, and vomiting |
|||
* Progresses to severe encephalitis |
|||
== Diagnosis == |
|||
* Serologic with IgM, using screening ELISA followed by confirmatory PRNT |
|||
== Management == |
== Management == |
||
* Supportive |
* Supportive |
||
== Prognosis == |
|||
* Mortality is 10%, with survivors having permanent neurologic sequelae |
|||
[[Category:Flaviviridae]] |
[[Category:Flaviviridae]] |
||
Revision as of 01:38, 14 February 2020
- Tick-borne viral infection that can cause encephalitis
- Closely related to deer tick virus
- Named for Pawassan, Ontario, but endemic in Eurasia and North America
Background
Microbiology
- Single-stranded positive-sense RNA virus in the genus Flavivirus, family Flaviviridae
- Two genotypes: lineage 1 and lineage 2
Epidemiology
- Transmitted by a number of Ixodes and Dermacentor ticks
Presentation
- Incubation period 1 to 3 weeks
- Fever, headache, confusion, weakness, encephalopathy, focal neurological deficits, and vomiting
- Progresses to severe encephalitis
Diagnosis
- Serologic with IgM, using screening ELISA followed by confirmatory PRNT
Management
- Supportive
Prognosis
- Mortality is 10%, with survivors having permanent neurologic sequelae
