Pitt bacteremia score: Difference between revisions

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* Originally developed to predict mortality with [[Pseudomonas aeruginosa]] [[bacteremia]]
* Originally developed to predict mortality with [[Pseudomonas aeruginosa]] [[bacteremia]]
* Now used more broadly for mortality from infections more generally
* Now used more broadly for mortality from infections more generally
* A modified Pitt bacteremia score (mPBS) also exists<ref name=":0">Nakada-Motokawa, N, Miyazaki, T, Ueda, T, et al. Modified Pitt bacteremia score for predicting mortality in patients with candidaemia: A multicentre seven-year retrospective study conducted in Japan. ''Mycoses''. 2021; 64: 1498-1507. https://doi.org/10.1111/myc.13380</ref>


== Components ==
== Components ==
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{| class="wikitable"
{| class="wikitable"
!Criterion
!Criterion
!Points
!Points (original)
!Points (modified)
|-
|-
| colspan="2" |Fever (°C)
| colspan="3" |Fever (°C)
|-
|-
|&nbsp;&nbsp;&nbsp;&nbsp;≤35 or ≥40
|&nbsp;&nbsp;&nbsp;&nbsp;≤35 or ≥40
|2
|2
|
|-
|-
|&nbsp;&nbsp;&nbsp;&nbsp;35.1-36.0 or 39.0-39.9
|&nbsp;&nbsp;&nbsp;&nbsp;35.1-36.0 or 39.0-39.9
|1
|1
|
|-
|-
|&nbsp;&nbsp;&nbsp;&nbsp;36.1-38.9
|&nbsp;&nbsp;&nbsp;&nbsp;36.1-38.9
|0
|0
|
|-
|-
|Hypotension: drop by >30 SBP or >20 DBP, or vasopressors, or SBP <90
|Hypotension: drop by >30 SBP or >20 DBP, or vasopressors, or SBP <90
|2
|2
|2
|-
|-
|Mechanical ventilation
|Mechanical ventilation
|2
|2
|2
|-
|-
|Cardiac arrest
|Cardiac arrest
|4
|4
|4
|-
|-
| colspan="2" |Mental status
| colspan="3" |Mental status
|-
|-
|&nbsp;&nbsp;&nbsp;&nbsp;Alert
|&nbsp;&nbsp;&nbsp;&nbsp;Alert
|0
|0
|0
|-
|-
|&nbsp;&nbsp;&nbsp;&nbsp;Disoriented
|&nbsp;&nbsp;&nbsp;&nbsp;Disoriented
|2
|1
|1
|-
|-
|&nbsp;&nbsp;&nbsp;&nbsp;Stuporous/comatose
|&nbsp;&nbsp;&nbsp;&nbsp;Stuporous/comatose
|2
|2
|-
|&nbsp;&nbsp;&nbsp;&nbsp;Comatose
|4
|4
|4
|-
|Dialysis
|
|2
|}
|}


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|+Mortality predicted by PBS for various infections.
|+Mortality predicted by PBS for various infections.
!Score
!Score
![[Staphylococcus aureus bacteremia|SAB]] (30-dy mortality)<ref>Roth JA, Tschudin-Sutter S, Dangel M, Frei R, Battegay M, Widmer AF. Value of the Pitt Bacteraemia Score to predict short-term mortality in Staphylococcus aureus bloodstream infection: a validation study. Swiss Med Wkly [Internet]. 2017 Aug. 10 [cited 2023 Feb. 8];147(3132):w14482. Available from: https://smw.ch/index.php/smw/article/view/2342</ref>
![[Staphylococcus aureus bacteremia|SAB]] (30-day mortality)<ref>Roth JA, Tschudin-Sutter S, Dangel M, Frei R, Battegay M, Widmer AF. Value of the Pitt Bacteraemia Score to predict short-term mortality in Staphylococcus aureus bloodstream infection: a validation study. Swiss Med Wkly [Internet]. 2017 Aug. 10 [cited 2023 Feb. 8];147(3132):w14482. Available from: https://smw.ch/index.php/smw/article/view/2342</ref>
!Nonbacteremic infections (14-day mortality)<ref>Heather Henderson, Courtney L Luterbach, Eric Cober, Sandra S Richter, Robert A Salata, Robert C Kalayjian, Richard R Watkins, Yohei Doi, Keith S Kaye, Scott Evans, Vance G Fowler, Jr, Robert A Bonomo, Anthony Harris, Sonia Napravnik, David Van Duin, The Pitt Bacteremia Score Predicts Mortality in Nonbacteremic Infections, ''Clinical Infectious Diseases'', Volume 70, Issue 9, 1 May 2020, Pages 1826–1833, https://doi.org/10.1093/cid/ciz528</ref>
!Nonbacteremic infections (14-day mortality)<ref>Heather Henderson, Courtney L Luterbach, Eric Cober, Sandra S Richter, Robert A Salata, Robert C Kalayjian, Richard R Watkins, Yohei Doi, Keith S Kaye, Scott Evans, Vance G Fowler, Jr, Robert A Bonomo, Anthony Harris, Sonia Napravnik, David Van Duin, The Pitt Bacteremia Score Predicts Mortality in Nonbacteremic Infections, ''Clinical Infectious Diseases'', Volume 70, Issue 9, 1 May 2020, Pages 1826–1833, https://doi.org/10.1093/cid/ciz528</ref>
!Candidemia (mPBS) (30-day mortality)<ref name=":0" />
|-
|-
|0
|0
|8%
|8%
| rowspan="4" |5%
|
| rowspan="4" |14%
|-
|-
|1
|1
|5%
|5%
|
|-
|-
|2
|2
|15%
|15%
|
|-
|-
|3
|3
|40%
|
|-
|<4
|
|5%
|-
|≥4
|
|40%
|40%
|-
|-
|4
|4
|47%
|47%
| rowspan="5" |40%
|
| rowspan="4" |37%
|-
|-
|5
|5
|33%
|33%
|
|-
|-
|6
|6
|43%
|43%
|
|-
|-
|7
|≥7
|75%
| rowspan="2" |75%
|
|-
|≥8
|69%
|}
|}
[[Category:Infectious diseases]]
[[Category:Infectious diseases]]

Revision as of 16:06, 28 July 2023

Background

  • Originally developed to predict mortality with Pseudomonas aeruginosa bacteremia
  • Now used more broadly for mortality from infections more generally
  • A modified Pitt bacteremia score (mPBS) also exists[1]

Components

  • Measured at onset of bacteremia
Criterion Points (original) Points (modified)
Fever (°C)
    ≤35 or ≥40 2
    35.1-36.0 or 39.0-39.9 1
    36.1-38.9 0
Hypotension: drop by >30 SBP or >20 DBP, or vasopressors, or SBP <90 2 2
Mechanical ventilation 2 2
Cardiac arrest 4 4
Mental status
    Alert 0 0
    Disoriented 1 1
    Stuporous/comatose 2 2
    Comatose 4 4
Dialysis 2

Interpretation

  • ≥4 usually used as a cutoff for increased risk of death
Mortality predicted by PBS for various infections.
Score SAB (30-day mortality)[2] Nonbacteremic infections (14-day mortality)[3] Candidemia (mPBS) (30-day mortality)[1]
0 8% 5% 14%
1 5%
2 15%
3 40%
4 47% 40% 37%
5 33%
6 43%
7 75%
≥8 69%
  1. 1.0 1.1 Nakada-Motokawa, N, Miyazaki, T, Ueda, T, et al. Modified Pitt bacteremia score for predicting mortality in patients with candidaemia: A multicentre seven-year retrospective study conducted in Japan. Mycoses. 2021; 64: 1498-1507. https://doi.org/10.1111/myc.13380
  2. Roth JA, Tschudin-Sutter S, Dangel M, Frei R, Battegay M, Widmer AF. Value of the Pitt Bacteraemia Score to predict short-term mortality in Staphylococcus aureus bloodstream infection: a validation study. Swiss Med Wkly [Internet]. 2017 Aug. 10 [cited 2023 Feb. 8];147(3132):w14482. Available from: https://smw.ch/index.php/smw/article/view/2342
  3. Heather Henderson, Courtney L Luterbach, Eric Cober, Sandra S Richter, Robert A Salata, Robert C Kalayjian, Richard R Watkins, Yohei Doi, Keith S Kaye, Scott Evans, Vance G Fowler, Jr, Robert A Bonomo, Anthony Harris, Sonia Napravnik, David Van Duin, The Pitt Bacteremia Score Predicts Mortality in Nonbacteremic Infections, Clinical Infectious Diseases, Volume 70, Issue 9, 1 May 2020, Pages 1826–1833, https://doi.org/10.1093/cid/ciz528