Blood culture contamination: Difference between revisions

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Almost never true bacteremia (almost always contaminant)
- Corynebacterium, except Corynebacterium jeikeium
- Bacillus, except Bacillus anthracis
- Cutibacterium acnes
Sometimes true bacteremia
Often true bacteremia
- Enterococcus
- Aerococcus
Always true bacteremia (or at least, always treated as such)
Coagulase-negative staphylococci are rarely significant (12%), but because they are so common (70-80% of all positive cultures), they are the most common cause of bacteremia

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-* ''Never'' bacteremia
+* '''Almost never''' true bacteremia (almost always contaminant)
-** ''Corynebacterium''
+** [[Corynebacterium]], except [[Corynebacterium jeikeium]]
-** ''Bacillus'', except ''B. anthracis''
+** [[Bacillus]], except [[Bacillus anthracis]]
-** ''Propionobacterium acnes''
+** [[Cutibacterium acnes]]
-* ''Almost never'' bacteremia
+* '''Sometimes''' true bacteremia
-** ''Micrococcus''
+** [[Micrococcus]]
+** [[Clostridium perfringens]]
-** ''Enterococcus''
+** [[Coagulase-negative staphylococci]]
-** ''Clostridium perfringens''
+** [[Viridans group streptococci]]
-** Coagulase-negative staphylococci
+** [[Lactobacillus]]
-* ''Always'' true bacteremia
+** [[Nutritionally variant streptococci]] ([[Abiotrophia]] and [[Granulicatella]])
-** ''Saphylococcus aureus''
+* '''Often''' true bacteremia
-** ''Streptococcus pneumoniae''
+** [[Enterococcus]]
-** ''Escherichia coli''
+** [[Aerococcus]]
-** Enterobacteraciae
+* '''Always''' true bacteremia (or at least, always treated as such)
-** ''Pseudomonas aeruginosa''
+** [[Staphylococcus aureus]]
-** ''Candida albicans''
+** [[Streptococcus pneumoniae]]
-* Coagulase negative staphylococci are rarely significant (12%), but because they are so common (70-80% of all positive cultures), they are the most common cause of bacteremia.
+** [[Escherichia coli]] and other [[Enterobacterales]]
+** [[Pseudomonas aeruginosa]]
+** [[Candida albicans]]
+* [[Coagulase-negative staphylococci]] are rarely significant (12%), but because they are so common (70-80% of all positive cultures), they are the most common cause of bacteremia
+== Further Reading ==
+* Laboratory approaches to determining blood culture contamination rates: an ASM Laboratory Practices Subcommittee report. ''J Clin Microbiol''. 2023;62:e01028-23. doi: [https://doi.org/10.1128/jcm.01028-23 10.1128/jcm.01028-23]
+[[Category:Microbiology]]