Pleural effusion in allogeneic hematopoietic stem cell transplantation: Difference between revisions

Latest revision as of 19:50, 26 January 2021

Background

Incidence of 16% in first 100 days post-transplant

Etiology

Infection (39%), often with concurrent bacteremia or fungemia
- Gram-positive bacteria
- Gram-negative bacteria
- Polymicrobial infections
- Candida albicans
- Mycobacterium tuberculosis
- CMV
- Legionella
- Rare: influenza, Aspergillus, mucormycosis, human metapneumovirus, human herpesvirus 6
Volume overload (24%)
Serositis-type GVHD (11%)
Others: malignant pleural effusion, engraftment syndrome, BOOP, congestive heart failure, idiopathic pneumonia syndrome, sinusoidal obstruction syndrome

@@ Line 1: / Line 1: @@
-== Background ==
+==Background==
-* Incidence of 16% in first 100 days post-transplant
+*Incidence of 16% in first 100 days post-transplant
-=== Etiology ===
+===Etiology===
-* Infection (39%), often with concurrent bacteremia or fungemia
+*Infection (39%), often with concurrent bacteremia or fungemia
-** Gram-positive bacteria
+**Gram-positive bacteria
-** Gram-negative bacteria
+**Gram-negative bacteria
-** Polymicrobial infections
+**Polymicrobial infections
-** [[Candida albicans]]
+**[[Candida albicans]]
-** [[Mycobacterium tuberculosis]]
+**[[Mycobacterium tuberculosis]]
-** [[CMV]]
+**[[CMV]]
-** [[Legionella]]
+**[[Legionella]]
-** Rare: [[influenza]], [[Aspergillus]], [[mucormycosis]], [[human metapneumovirus]], [[human herpesvirus 6]]
+**Rare: [[influenza]], [[Aspergillus]], [[mucormycosis]], [[human metapneumovirus]], [[human herpesvirus 6]]
-* Volume overload (24%)
+*Volume overload (24%)
-* Serositis-type [[GVHD]] (11%)
+*Serositis-type [[GVHD]] (11%)
-* Others: [[malignant pleural effusion]], engraftment syndrome, [[BOOP]], [[congestive heart failure]], idiopathic pneumonia syndrome, sinusoidal obstruction syndrome
+*Others: [[malignant pleural effusion]], engraftment syndrome, [[BOOP]], [[congestive heart failure]], idiopathic pneumonia syndrome, sinusoidal obstruction syndrome
+== Further Reading ==
+* Incidence, etiology, and outcome of pleural effusions in allogeneic hematopoietic stem cell transplantation. ''Am J Hematol''. 2016;91(9):E341-E347. doi: [https://doi.org/10.1002/ajh.24435 10.1002/ajh.24435]