Myasthenia gravis: Difference between revisions

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* Can also present with predominantly bulbar involvement, or simple ocular involvement
* Can also present with predominantly bulbar involvement, or simple ocular involvement


== Clinical Presentation ==
== Clinical Manifestations ==


* History
* History

Latest revision as of 11:15, 14 July 2020

Definition

  • A autoimmune disorder of the motor endplate that is associated with thymomas and causes a syndrome of weakness that worsens with repeated movements
  • Can also present with predominantly bulbar involvement, or simple ocular involvement

Clinical Manifestations

  • History
  • Signs & Symptoms
    • Ptosis worse than baseline
    • Abnormal or fatiguable extraocular movements
    • Dysarthria
    • Neck flexion and extension (tests C3-4 that also innervates the diaphragm)
    • Decreased duration of limb raiding

Management

  • Acute
    • Monitor FVC, MIPS, and MEPS
      • Can approximate FVC by counting the duration of exhilation
  • Chronic