Visceral larva migrans: Difference between revisions

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==Background==
* Organisms that cause VLM include: {{#ask: [[Causes::visceral larva migrans]] | default=none}}
{| class="wikitable"
!Organism
!Host
!Notes
|-
|[[Toxocara canis]]
|canines
|most common cause in humans
|-
|[[Toxocara cati]]
|felines
|
|-
|[[Baylisascaris procyonis]]
|raccoons
|causes neural larva migrans
|}

*Humans are dead-end hosts

==Clinical Manifestations==

*Most frequently in young children (who are effective at getting dirt into their mouths)
**Mean age 2 to 4 years
*Most infection is asymptomatic
*Severe symptoms [[Causes::eosinophilia]], [[Causes::fever]], and [[Causes::hepatomegaly]]
*Other common symptoms include [[Causes::cough]], [[Causes::wheezing]]
*Rarely, urticaria and nodules
*Very rarely, ocular involvement

==Different Diagnosis==

*Other parasites
**[[Baylisascaris procyonis]]
**[[Schistosomiasis|Acute schistosomiasis]]
**[[Fasciola hepatica]], [[Clonorchis sinensis]], and [[Opisthorchis viverrini]]
**[[Ascaris lumbricoides]] liver abscess
**[[Echinococcus]]
**[[Capillaria hepatica]]
*Other diseases

==Diagnosis==

*Mostly clinical ± serology
*May be able to see larvae on tissue histopathology

==Management==

*For mild or moderate disease, clinical monitoring is all that is needed as it self-resolves in most cases
*For severe or life-threatening disease, can try treating with [[Is treated by::albendazole]], [[Is treated by::mebendazole]], [[Is treated by::diethylcarbamazine]]
**Adjunctive corticosteroids are used due to intense inflammatory reaction to dying parasites

==Prevention==

*Do not eat dog, cat, or raccoon poop
*Keep sandboxes closed when not in use, and keep pets away from them
*Test and treat dogs regularly

[[Category:Infectious diseases]]

Latest revision as of 17:55, 20 August 2020

Background

Organism Host Notes
Toxocara canis canines most common cause in humans
Toxocara cati felines
Baylisascaris procyonis raccoons causes neural larva migrans
  • Humans are dead-end hosts

Clinical Manifestations

  • Most frequently in young children (who are effective at getting dirt into their mouths)
    • Mean age 2 to 4 years
  • Most infection is asymptomatic
  • Severe symptoms eosinophilia, fever, and hepatomegaly
  • Other common symptoms include cough, wheezing
  • Rarely, urticaria and nodules
  • Very rarely, ocular involvement

Different Diagnosis

Diagnosis

  • Mostly clinical ± serology
  • May be able to see larvae on tissue histopathology

Management

  • For mild or moderate disease, clinical monitoring is all that is needed as it self-resolves in most cases
  • For severe or life-threatening disease, can try treating with albendazole, mebendazole, diethylcarbamazine
    • Adjunctive corticosteroids are used due to intense inflammatory reaction to dying parasites

Prevention

  • Do not eat dog, cat, or raccoon poop
  • Keep sandboxes closed when not in use, and keep pets away from them
  • Test and treat dogs regularly