Blood culture contamination: Difference between revisions

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Almost never true bacteremia (almost always contaminant)
- Corynebacterium, except Corynebacterium jeikeium
- Bacillus, except Bacillus anthracis
- Cutibacterium acnes
Sometimes true bacteremia
Often true bacteremia
- Enterococcus
- Aerococcus
Always true bacteremia (or at least, always treated as such)
Coagulase-negative staphylococci are rarely significant (12%), but because they are so common (70-80% of all positive cultures), they are the most common cause of bacteremia

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-* '''Never''' bacteremia
+* '''Almost never''' true bacteremia (almost always contaminant)
-** ''[[Corynebacterium]]''
+** [[Corynebacterium]], except [[Corynebacterium jeikeium]]
-** ''[[Bacillus]]'', except ''B. anthracis''
+** [[Bacillus]], except [[Bacillus anthracis]]
-** ''[[Propionobacterium acnes]]''
+** [[Cutibacterium acnes]]
-* '''Almost never''' bacteremia
+* '''Sometimes''' true bacteremia
-** ''[[Micrococcus]]''
+** [[Micrococcus]]
-** ''[[Enterococcus]]''
+** [[Clostridium perfringens]]
-** ''[[Clostridium perfringens]]''
 ** [[Coagulase-negative staphylococci]]
+** [[Viridans group streptococci]]
-* '''Always''' true bacteremia
-** ''[[Staphylococcus aureus]]''
+** [[Lactobacillus]]
+** [[Nutritionally variant streptococci]] ([[Abiotrophia]] and [[Granulicatella]])
-** ''[[Streptococcus pneumoniae]]''
+* '''Often''' true bacteremia
-** ''[[Escherichia coli]]''
+** [[Enterococcus]]
-** Enterobacteraciae
-** ''[[Pseudomonas aeruginosa]]''
+** [[Aerococcus]]
+* '''Always''' true bacteremia (or at least, always treated as such)
-** ''[[Candida albicans]]''
+** [[Staphylococcus aureus]]
-* Coagulase-negative staphylococci are rarely significant (12%), but because they are so common (70-80% of all positive cultures), they are the most common cause of bacteremia.
+** [[Streptococcus pneumoniae]]
+** [[Escherichia coli]] and other [[Enterobacterales]]
+** [[Pseudomonas aeruginosa]]
+** [[Candida albicans]]
+* [[Coagulase-negative staphylococci]] are rarely significant (12%), but because they are so common (70-80% of all positive cultures), they are the most common cause of bacteremia
+== Further Reading ==
+* Laboratory approaches to determining blood culture contamination rates: an ASM Laboratory Practices Subcommittee report. ''J Clin Microbiol''. 2023;62:e01028-23. doi: [https://doi.org/10.1128/jcm.01028-23 10.1128/jcm.01028-23]
 [[Category:Microbiology]]