Antibiotic spectrum index: Difference between revisions

From IDWiki
m (added links)
(added spectrum table)
Line 5: Line 5:
** [[Enterococcus faecalis]]
** [[Enterococcus faecalis]]
** Vancomycin-resistant [[Enterococcus faecalis]] (VRE)
** Vancomycin-resistant [[Enterococcus faecalis]] (VRE)
** [[Escherichia coli]] and [[Klebsiella]]
** [[Escherichia coli]] or [[Klebsiella]]
** [[AmpC β-lactamase|AmpC producers]]
** [[AmpC β-lactamase|AmpC producers]] ([[Enterobacter]], [[Serratia]], and [[Citrobacter]])
** [[Extended-spectrum β-lactamases|Extended-spectrum β-lactamase]] (ESBL) E. coli/Klebsiella
** [[Extended-spectrum β-lactamases|Extended-spectrum β-lactamase]] (ESBL) [[Escherichia coli|E. coli]]/[[Klebsiella]]
** [[Pseudomonas aeruginosa]]
** [[Pseudomonas aeruginosa]]
** Penicillin-resistant [[pneumococcus]] (PRP)
** Penicillin-resistant [[pneumococcus]] (PRP)
** [[Moraxella]] and [[Haemophilus influenzae]]
** [[Moraxella]] and [[Haemophilus influenzae]]
** [[Mycoplasma]] and [[Chlamydophila]]
** [[Mycoplasma]] and [[Chlamydophila]]
** [[Anaerobes]] (1 point; 2 points for [[Bacteriodes fragilis]])
** [[Anaerobes]] (in general)
** [[Bacteriodes fragilis]] (specifically)
** Multidrug-resistant organisms
* For each patient, the number of points for every antibiotic is added to give a total daily ASI

== Spectrum Indices ==
{| class="wikitable"
!Antibiotic
!MSSA
!Enterococcus
!Anaerobes
!Bacteroides
!Moraxella/Haemophilus
!Escherichia/Klebsiella
!AmpC
!ESBL
!Pseudomonas
!MRSA
!Pen-R pneumococcus
!VRE
!Atypical
!MDRO
!ASI
|-
|Dicloxacillin
|1
|0
|0
|0
|0
|0
|0
|0
|0
|0
|0
|0
|0
|0
|1
|-
|Oxacillin
|1
|0
|0
|0
|0
|0
|0
|0
|0
|0
|0
|0
|0
|0
|1
|-
|Amoxicillin
|0
|1
|0
|0
|0
|1
|0
|0
|0
|0
|0
|0
|0
|0
|2
|-
|Ampicillin
|0
|1
|0
|0
|0
|1
|0
|0
|0
|0
|0
|0
|0
|0
|2
|-
|Cephalexin
|1
|0
|0
|0
|0
|1
|0
|0
|0
|0
|0
|0
|0
|0
|2
|-
|Erythromycin
|0
|0
|0
|0
|1
|0
|0
|0
|0
|0
|0
|0
|1
|0
|2
|-
|Erythromycin
|0
|0
|0
|0
|1
|0
|0
|0
|0
|0
|0
|0
|1
|0
|2
|-
|Metronidazole
|0
|0
|1
|1
|0
|0
|0
|0
|0
|0
|0
|0
|0
|0
|2
|-
|Penicillin
|0
|1
|1
|0
|0
|0
|0
|0
|0
|0
|0
|0
|0
|0
|2
|-
|Aztreonam
|0
|0
|0
|0
|1
|1
|0
|0
|1
|0
|0
|0
|0
|0
|3
|-
|Cefazolin
|1
|0
|0
|0
|1
|1
|0
|0
|0
|0
|0
|0
|0
|0
|3
|-
|Cefdinir
|1
|0
|0
|0
|1
|1
|0
|0
|0
|0
|0
|0
|0
|0
|3
|-
|Cefixime
|0
|0
|1
|0
|1
|1
|0
|0
|0
|0
|0
|0
|0
|0
|3
|-
|Cefpodoxime
|1
|0
|0
|0
|1
|1
|0
|0
|0
|0
|0
|0
|0
|0
|3
|-
|Rifampin
|1
|0
|0
|0
|1
|0
|0
|0
|0
|1
|0
|0
|0
|0
|3
|-
|Azithromycin
|1
|0
|1
|0
|1
|0
|0
|0
|0
|0
|0
|0
|1
|0
|4
|-
|Cefprozil
|1
|0
|1
|0
|1
|1
|0
|0
|0
|0
|0
|0
|0
|0
|4
|-
|Ceftazidime
|0
|0
|1
|0
|1
|1
|0
|0
|1
|0
|0
|0
|0
|0
|4
|-
|Cefuroxime
|1
|0
|1
|0
|1
|1
|0
|0
|0
|0
|0
|0
|0
|0
|4
|-
|Chloramphenicol
|0
|0
|1
|1
|1
|1
|0
|0
|0
|0
|0
|0
|0
|0
|4
|-
|Clarithromycin
|1
|0
|1
|0
|1
|0
|0
|0
|0
|0
|0
|0
|1
|0
|4
|-
|Clindamycin
|1
|0
|1
|1
|0
|0
|0
|0
|0
|1
|0
|0
|0
|0
|4
|-
|Piperacillin
|0
|1
|1
|0
|0
|1
|0
|0
|1
|0
|0
|0
|0
|0
|4
|-
|Trimethoprim- sulfamethoxazole
|1
|0
|0
|0
|1
|1
|0
|0
|0
|1
|0
|0
|0
|0
|4
|-
|Cefotaxime
|1
|0
|1
|0
|1
|1
|0
|0
|0
|0
|1
|0
|0
|0
|5
|-
|Cefoxitin
|1
|0
|1
|1
|1
|1
|0
|0
|0
|0
|0
|0
|0
|0
|5
|-
|Ceftriaxone
|1
|0
|1
|0
|1
|1
|0
|0
|0
|0
|1
|0
|0
|0
|5
|-
|Colistimethate
|0
|0
|0
|0
|0
|1
|1
|1
|1
|0
|0
|0
|0
|1
|5
|-
|Daptomycin
|1
|1
|0
|0
|0
|0
|0
|0
|0
|1
|0
|1
|0
|1
|5
|-
|Doxycycline
|1
|0
|0
|0
|1
|1
|0
|0
|0
|1
|0
|0
|1
|0
|5
|-
|Gentamicin
|1
|0
|0
|0
|1
|1
|0
|0
|1
|1
|0
|0
|0
|0
|5
|-
|Minocycline
|1
|0
|0
|0
|1
|1
|0
|0
|0
|1
|0
|0
|1
|0
|5
|-
|Telavancin
|1
|1
|0
|0
|0
|0
|0
|0
|0
|1
|1
|0
|0
|1
|5
|-
|Tobramycin
|1
|0
|0
|0
|1
|1
|0
|0
|1
|1
|0
|0
|0
|0
|5
|-
|Vancomycin
|1
|1
|0
|0
|0
|0
|0
|0
|0
|1
|1
|0
|0
|1
|5
|-
|Amikacin sulfate
|1
|0
|0
|0
|1
|1
|0
|0
|1
|1
|0
|0
|0
|1
|6
|-
|Amoxicillin-clavulanate
|1
|1
|1
|1
|1
|1
|0
|0
|0
|0
|0
|0
|0
|0
|6
|-
|Ampicillin-sulbactam
|1
|1
|1
|1
|1
|1
|0
|0
|0
|0
|0
|0
|0
|0
|6
|-
|Cefepime
|1
|0
|0
|0
|1
|1
|1
|0
|1
|0
|1
|0
|0
|0
|6
|-
|Linezolid
|1
|1
|0
|0
|0
|0
|0
|0
|0
|1
|1
|1
|0
|1
|6
|-
|Ticarcillin-clavulanate
|1
|0
|1
|1
|1
|1
|0
|0
|1
|0
|0
|0
|0
|0
|6
|-
|Ceftaroline
|1
|1
|0
|0
|1
|1
|1
|0
|0
|1
|1
|0
|0
|1
|8
|-
|Ciprofloxacin
|1
|1
|0
|0
|1
|1
|1
|1
|1
|0
|0
|0
|1
|0
|8
|-
|Piperacillin-tazobactam
|1
|1
|1
|1
|1
|1
|1
|0
|1
|0
|0
|0
|0
|0
|8
|-
|Ertapenem
|1
|0
|1
|1
|1
|1
|1
|1
|0
|0
|1
|0
|0
|1
|9
|-
|Levofloxacin
|1
|1
|1
|0
|1
|1
|1
|1
|0
|0
|1
|0
|1
|0
|9
|-
|Meropenem
|1
|0
|1
|1
|1
|1
|1
|1
|1
|0
|1
|0
|0
|1
|10
|-
|Moxifloxacin
|1
|1
|1
|1
|1
|1
|1
|0
|0
|1
|1
|0
|1
|0
|10
|-
|Imipenem-cilastatin
|1
|1
|1
|1
|1
|1
|1
|1
|1
|0
|1
|0
|0
|1
|11
|-
|Tigecycline
|1
|1
|1
|1
|1
|1
|1
|1
|0
|1
|1
|1
|1
|1
|13
|}


==Further Reading==
==Further Reading==

Revision as of 12:13, 22 September 2022

Spectrum Indices

Antibiotic MSSA Enterococcus Anaerobes Bacteroides Moraxella/Haemophilus Escherichia/Klebsiella AmpC ESBL Pseudomonas MRSA Pen-R pneumococcus VRE Atypical MDRO ASI
Dicloxacillin 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1
Oxacillin 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1
Amoxicillin 0 1 0 0 0 1 0 0 0 0 0 0 0 0 2
Ampicillin 0 1 0 0 0 1 0 0 0 0 0 0 0 0 2
Cephalexin 1 0 0 0 0 1 0 0 0 0 0 0 0 0 2
Erythromycin 0 0 0 0 1 0 0 0 0 0 0 0 1 0 2
Erythromycin 0 0 0 0 1 0 0 0 0 0 0 0 1 0 2
Metronidazole 0 0 1 1 0 0 0 0 0 0 0 0 0 0 2
Penicillin 0 1 1 0 0 0 0 0 0 0 0 0 0 0 2
Aztreonam 0 0 0 0 1 1 0 0 1 0 0 0 0 0 3
Cefazolin 1 0 0 0 1 1 0 0 0 0 0 0 0 0 3
Cefdinir 1 0 0 0 1 1 0 0 0 0 0 0 0 0 3
Cefixime 0 0 1 0 1 1 0 0 0 0 0 0 0 0 3
Cefpodoxime 1 0 0 0 1 1 0 0 0 0 0 0 0 0 3
Rifampin 1 0 0 0 1 0 0 0 0 1 0 0 0 0 3
Azithromycin 1 0 1 0 1 0 0 0 0 0 0 0 1 0 4
Cefprozil 1 0 1 0 1 1 0 0 0 0 0 0 0 0 4
Ceftazidime 0 0 1 0 1 1 0 0 1 0 0 0 0 0 4
Cefuroxime 1 0 1 0 1 1 0 0 0 0 0 0 0 0 4
Chloramphenicol 0 0 1 1 1 1 0 0 0 0 0 0 0 0 4
Clarithromycin 1 0 1 0 1 0 0 0 0 0 0 0 1 0 4
Clindamycin 1 0 1 1 0 0 0 0 0 1 0 0 0 0 4
Piperacillin 0 1 1 0 0 1 0 0 1 0 0 0 0 0 4
Trimethoprim- sulfamethoxazole 1 0 0 0 1 1 0 0 0 1 0 0 0 0 4
Cefotaxime 1 0 1 0 1 1 0 0 0 0 1 0 0 0 5
Cefoxitin 1 0 1 1 1 1 0 0 0 0 0 0 0 0 5
Ceftriaxone 1 0 1 0 1 1 0 0 0 0 1 0 0 0 5
Colistimethate 0 0 0 0 0 1 1 1 1 0 0 0 0 1 5
Daptomycin 1 1 0 0 0 0 0 0 0 1 0 1 0 1 5
Doxycycline 1 0 0 0 1 1 0 0 0 1 0 0 1 0 5
Gentamicin 1 0 0 0 1 1 0 0 1 1 0 0 0 0 5
Minocycline 1 0 0 0 1 1 0 0 0 1 0 0 1 0 5
Telavancin 1 1 0 0 0 0 0 0 0 1 1 0 0 1 5
Tobramycin 1 0 0 0 1 1 0 0 1 1 0 0 0 0 5
Vancomycin 1 1 0 0 0 0 0 0 0 1 1 0 0 1 5
Amikacin sulfate 1 0 0 0 1 1 0 0 1 1 0 0 0 1 6
Amoxicillin-clavulanate 1 1 1 1 1 1 0 0 0 0 0 0 0 0 6
Ampicillin-sulbactam 1 1 1 1 1 1 0 0 0 0 0 0 0 0 6
Cefepime 1 0 0 0 1 1 1 0 1 0 1 0 0 0 6
Linezolid 1 1 0 0 0 0 0 0 0 1 1 1 0 1 6
Ticarcillin-clavulanate 1 0 1 1 1 1 0 0 1 0 0 0 0 0 6
Ceftaroline 1 1 0 0 1 1 1 0 0 1 1 0 0 1 8
Ciprofloxacin 1 1 0 0 1 1 1 1 1 0 0 0 1 0 8
Piperacillin-tazobactam 1 1 1 1 1 1 1 0 1 0 0 0 0 0 8
Ertapenem 1 0 1 1 1 1 1 1 0 0 1 0 0 1 9
Levofloxacin 1 1 1 0 1 1 1 1 0 0 1 0 1 0 9
Meropenem 1 0 1 1 1 1 1 1 1 0 1 0 0 1 10
Moxifloxacin 1 1 1 1 1 1 1 0 0 1 1 0 1 0 10
Imipenem-cilastatin 1 1 1 1 1 1 1 1 1 0 1 0 0 1 11
Tigecycline 1 1 1 1 1 1 1 1 0 1 1 1 1 1 13

Further Reading

  • Development and Application of an Antibiotic Spectrum Index for Benchmarking Antibiotic Selection Patterns Across Hospitals. Infect Control Hosp Epidemiol. 2017;38(8):993-997. doi: 10.1017/ice.2017.94.
Retrieved from "https://idwiki.org/index.php?title=Antibiotic_spectrum_index&oldid=9424"
Powered by MediaWiki
Powered by Semantic MediaWiki