Asplenia and hyposplenia: Difference between revisions
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(Created page with "== Background == * Spleen is an important part of the immune system, particularly for encapsulated organisms * Increased risk for severe sepsis * Particularly increased risk for infection with: ** Streptococcus pneumoniae ** Haemophilus influenzae ** Neisseria meningitidis ** Capnocytophaga ** Bordatella holmesii ** Babesia ** Plasmodium falciparum == Management == * Cornerstone of management is prevention with vaccination ** Refer to Imm...") Â |
(→â€: added prophylaxis and pill in pocket options)  |
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* Cornerstone of management is prevention with vaccination |
* Cornerstone of management is prevention with vaccination |
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** Refer to [[Immunization of people with asplenia and hyposplenia]] |
** Refer to [[Immunization of people with asplenia and hyposplenia]] |
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* Patients may also benefit from prophylaxis with twice-daily [[penicillin]], [[amoxicillin]], or [[cephalexin]], or once-daily [[azithromycin]] |
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* Patients should also have pill-in-pocket broad-spectrum antibiotics to be taken in case of fever |
* Patients should also have pill-in-pocket broad-spectrum antibiotics to be taken in case of fever, such as [[amoxicillin-clavulanic acid]] or a respiratory fluoroquinolone |
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[[Category:Hematology]] |
[[Category:Hematology]] |
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Latest revision as of 14:26, 17 August 2022
Background
- Spleen is an important part of the immune system, particularly for encapsulated organisms
- Increased risk for severe sepsis
- Particularly increased risk for infection with:
Management
- Cornerstone of management is prevention with vaccination
- Patients may also benefit from prophylaxis with twice-daily penicillin, amoxicillin, or cephalexin, or once-daily azithromycin
- Patients should also have pill-in-pocket broad-spectrum antibiotics to be taken in case of fever, such as amoxicillin-clavulanic acid or a respiratory fluoroquinolone
