Etanercept: Difference between revisions
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Created page with "* Small-molecule TNF-α inhibitor * Dimeric fusion protein of a portion of the TNFR2 attached to the fC domain of human IgG1 * Indications include [[JRA]..." |
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Latest revision as of 00:50, 17 March 2022
- Small-molecule TNF-α inhibitor
- Dimeric fusion protein of a portion of the TNFR2 attached to the fC domain of human IgG1
- Indications include JRA, RA, ankylosing spondylitis, psoriatic arthritis, and plaque psoriasis
- Infectious complications include TB, NTM, and listeriosis, as well as other granulomatous diseases including histoplasmosis, candidiasis, aspergillosis, cryptococcosis, nocardiosis, and salmonellosis
- Likely lower risk of TB than monoclonal antibody inhibitors of TNF-α
