Tuberculoma: Difference between revisions
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==Background== |
==Background== |
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** Cerebral tuberculomas are more common in patients with [[HIV]]<br /> |
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==Clinical Manifestations== |
==Clinical Manifestations== |
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* Often asymptomatic |
* Often asymptomatic |
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*Most commonly presents in conjunction with [[tuberculous meningitis]], though can present alone |
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* In CNS, may present with headache, seizures, or focal neurological deficits |
* In CNS, may present with headache, seizures, or focal neurological deficits |
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Revision as of 14:13, 6 January 2022
Background
- Cerebral tuberculomas are more common in patients with HIV
- Cerebral tuberculomas are more common in patients with HIV
Clinical Manifestations
- Often asymptomatic
- Most commonly presents in conjunction with tuberculous meningitis, though can present alone
- In CNS, may present with headache, seizures, or focal neurological deficits
Differential Diagnosis
Diagnosis
- Based on imaging, with ring-enhancing lesion with surrounding edema
- If there is uncertainty about the diagnosis, may need biopsy
Management
- Manage per primary diagnosis, with at least 6 months of standard therapy
- Dexamethasone can be considered for CNS tuberculoma with surrounding vasogenic edema and neurologic symptoms
References
- ^ Deborah J Nicolls, Mark King, David Holland, Jennifer Bala, Carlos del Rio. Intracranial tuberculomas developing while on therapy for pulmonary tuberculosis. The Lancet Infectious Diseases. 2005;5(12):795-801. doi:10.1016/s1473-3099(05)70299-1.
