Recurrent meningitis: Difference between revisions
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==Differential Diagnosis== |
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*Immune defects |
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**[[Asplenia]] |
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**[[Hypogammaglobulinemia]] |
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**[[Complement deficiencies]], including [[properdin deficiency]], [[terminal complement deficiency]], and use of [[eculizumab]] |
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** Complement deficiences |
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*Parameningeal focus of infection |
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*Structural abnormalities |
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**Post-neurosurgery |
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**[[CSF leak]] or [[CSF fistula]] |
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**[[Dermal sinus]] |
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**[[Epidermoid cyst]] |
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**[[Craniopharyngioma]] |
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*Drugs |
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**[[TMP-SMX]] |
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** Septra |
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**[[NSAIDs]] |
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**[[IVIg]] |
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**OKT3 |
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**[[Phenytoin]] |
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*Infections |
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**[[HSV-2]] (Mollaret's disease) |
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*Inflammatory |
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**[[SLE]] |
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**[[Behçet disease]] |
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** Behcet's |
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==Specific Patients== |
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===Terminal Complement Deficiency=== |
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*Prone to recurrent [[Neisseria species|neisserial infections]] |
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[[Category:CNS infections]] |
[[Category:CNS infections]] |
Latest revision as of 22:01, 13 September 2020
Differential Diagnosis
- Immune defects
- Asplenia
- Hypogammaglobulinemia
- Complement deficiencies, including properdin deficiency, terminal complement deficiency, and use of eculizumab
- Parameningeal focus of infection
- Structural abnormalities
- Post-neurosurgery
- CSF leak or CSF fistula
- Dermal sinus
- Epidermoid cyst
- Craniopharyngioma
- Drugs
- Infections
- HSV-2 (Mollaret's disease)
- Inflammatory
Specific Patients
Terminal Complement Deficiency
- Prone to recurrent neisserial infections
Hypogammaglobulinemia
- Can develop chronic meningoencephalitis, primarily cause by: