Recurrent meningitis: Difference between revisions

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==Differential Diagnosis==
= Recurrent meningitis =


*Immune defects
== Differential Diagnosis ==
**[[Asplenia]]
**[[Hypogammaglobulinemia]]
**[[Complement deficiencies]], including [[properdin deficiency]], [[terminal complement deficiency]], and use of [[eculizumab]]
*Parameningeal focus of infection
*Structural abnormalities
**Post-neurosurgery
**[[CSF leak]] or [[CSF fistula]]
**[[Dermal sinus]]
**[[Epidermoid cyst]]
**[[Craniopharyngioma]]
*Drugs
**[[TMP-SMX]]
**[[NSAIDs]]
**[[IVIg]]
**OKT3
**[[Phenytoin]]
*Infections
**[[HSV-2]] (Mollaret's disease)
*Inflammatory
**[[SLE]]
**[[Behçet disease]]


==Specific Patients==
* Immune defects
** Asplenia
** Hypogammaglobulinemia
** Complement deficiences
* Parameningeal focis of infection
* Structurel abnormalities
** Post-neurosurgery
** CSF leak or fistula
** Dermal sinuses
** Epidermoid cysts
** Craniopharyngioma
* Drugs
** Septra
** NSAIDs
** IVIg
** OKT3
** Phenytoin
* Infections
** HSV (Mollaret's disease)
* Inflammatory
** SLE
** Behcet's


===Terminal Complement Deficiency===
== Hypogammaglobulinemia ==


*Prone to recurrent [[Neisseria species|neisserial infections]]
Can develop chronic meningoencephalitis, primarily cause by:


===Hypogammaglobulinemia===
* Enterovirus

* Mycoplasma
*Can develop chronic meningoencephalitis, primarily cause by:
**[[Enterovirus]]
**[[Mycoplasma]]

[[Category:CNS infections]]

Latest revision as of 22:01, 13 September 2020

Differential Diagnosis

Specific Patients

Terminal Complement Deficiency

Hypogammaglobulinemia